SCHEMBL6760764

SCHEMBL6760764

Oc1ccc(Nc2ccccc2O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.55
KMT2A Q03164 6/20 0.55
GAA P10253 6/20 0.55
MEN1 O00255 5/20 0.55
MAPK1 P28482 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
PKM P14618 1/20 0.55
CXCR2 P25025 2/20 0.53
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 2/20 0.52
THRB P10828 1/20 0.52
ALOX12 P18054 1/20 0.52
LMNA P02545 3/20 0.48
HTT P42858 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
POLB P06746 2/20 0.48
RECQL P46063 2/20 0.48
PRKD3 O94806 1/20 0.44
ABL1 P00519 1/20 0.44
EGFR P00533 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1920750 0.93 CXCR2 (0.59) MAPTKMT2AGAAMEN1MAPK1
SCHEMBL1921924 0.88 MAPT (0.60) MAPTKMT2AGAAMEN1MAPK1
SCHEMBL1921886 0.86 CXCR2 (0.53) MAPTKMT2AGAAMEN1MAPK1
SCHEMBL11000813 0.86 CXCR2 (0.63) MAPTKMT2AGAAMEN1MAPK1
SCHEMBL1008928 0.86 CXCR2 (0.68) MAPTKMT2AGAAMEN1MAPK1
SCHEMBL29720861 0.86 CXCR2 (0.68) MAPTKMT2AGAAMEN1MAPK1
SCHEMBL27435565 0.84 CXCR2 (0.66) MAPTKMT2AGAAMEN1MAPK1
SCHEMBL9566028 0.83 CXCR2 (0.50) MAPTKMT2AGAAMEN1MAPK1
SCHEMBL19185367 0.83 MAPT (0.64) MAPTKMT2AGAAMEN1MAPK1
SCHEMBL30686692 0.83 MAPT (0.60) MAPTKMT2AGAAMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112159327-A Compound for inhibiting proliferation of human cancer cells in nude mice 浙江大学 2021-01-01 CN claimed
CN-106748829-A A kind of compound for promoting human cancer cell that apoptosis occurs and its application 浙江大学 2017-05-31 CN claimed
WO-2002051962-A1 USE OF A COMPOSITION BASED ON A DIPHENYLAMINE DERIVATIVE FOR INHIBITING FREE RADICAL POLYMERISATION OF ETHYLENICALLY UNSATURATED AROMATIC MONOMERS RHODIA CHIMIE (FR) 2002-07-04 WO claimed
EP-1140772-A1 COMPOSITION AND METHOD FOR INHIBITING RADICAL POLYMERISATION OF ETHYLENICALLY UNSATURATED ALIPHATIC MONOMERS RHODIA CHIMIE (FR) 2001-10-10 EP claimed
WO-2000037412-A1 COMPOSITION AND METHOD FOR INHIBITING RADICAL POLYMERISATION OF ETHYLENICALLY UNSATURATED ALIPHATIC MONOMERS RHODIA CHIMIE (FR) 2000-06-29 WO claimed
CN-112159327-A Compound for inhibiting proliferation of human cancer cells in nude mice 浙江大学 2021-01-01 CN disclosed
CN-112159327-A Compound for inhibiting proliferation of human cancer cells in nude mice 浙江大学 2021-01-01 CN disclosed
WO-2017164260-A1 BENZOXAZINE COMPOUND, METHOD FOR PRODUCING SAME, AND BENZOXAZINE RESIN 学校法人近畿大学 2017-09-28 WO disclosed
CN-106748829-A A kind of compound for promoting human cancer cell that apoptosis occurs and its application 浙江大学 2017-05-31 CN disclosed
US-20040048207-A1 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2004-03-11 US disclosed
US-20030235792-A1 Silver halide photographic light-sensitive materials and method for development of the same FUJIFILM CORPORATION (JP) 2003-12-25 US disclosed
US-20030228547-A1 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2003-12-11 US disclosed
WO-2002051962-A1 USE OF A COMPOSITION BASED ON A DIPHENYLAMINE DERIVATIVE FOR INHIBITING FREE RADICAL POLYMERISATION OF ETHYLENICALLY UNSATURATED AROMATIC MONOMERS RHODIA CHIMIE (FR) 2002-07-04 WO disclosed
EP-1140772-A1 COMPOSITION AND METHOD FOR INHIBITING RADICAL POLYMERISATION OF ETHYLENICALLY UNSATURATED ALIPHATIC MONOMERS RHODIA CHIMIE (FR) 2001-10-10 EP disclosed
WO-2000037412-A1 COMPOSITION AND METHOD FOR INHIBITING RADICAL POLYMERISATION OF ETHYLENICALLY UNSATURATED ALIPHATIC MONOMERS RHODIA CHIMIE (FR) 2000-06-29 WO disclosed