Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 13/20 | 1.00 |
| ▸ | RAB9A | P51151 | 11/20 | 1.00 |
| ▸ | NPC1 | O15118 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.70 |
| ▸ | RELA | Q04206 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2752138 | 0.98 | EPHX1 (0.97) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| Bicarbonate SCHEMBL4208655 | 0.95 | EPHX1 (0.91) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13756244 | 0.91 | EPHX1 (0.86) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13756248 | 0.89 | EPHX1 (0.83) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12474945 | 0.85 | EPHX1 (0.74) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15612242 | 0.85 | EPHX1 (0.74) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12196184 | 0.85 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8391687 | 0.85 | EPHX1 (1.00) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16825746 | 0.84 | EPHX1 (0.72) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24988039 | 0.83 | EPHX1 (0.73) | EPHX1RAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024246857-A1 | UREA COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING ASTHMA AND PARKINSON'S DISEASE | INNOPHARMASCREEN INC. (KR) | 2024-12-05 | — | — | WO | disclosed |
| CN-109627429-B | Preparation method of high molecular weight poly (gamma-butyrolactone) | 青岛博远高分子材料研究院有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-114369232-B | Renewable degradable thermoplastic elastomer and preparation method thereof | 青岛科技大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-116789943-A | Unsaturated polylactic acid copolyester and preparation method thereof | 浙江恒逸石化研究院有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-114369232-A | Renewable degradable thermoplastic elastomer and preparation method thereof | 青岛科技大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-110804163-B | Preparation method of bio-based copolyester containing modifiable functional group | 青岛科技大学 | 2022-03-15 | — | — | CN | disclosed |
| EP-3215142-B1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2021-03-24 | — | — | EP | disclosed |
| WO-2020083180-A1 | METHOD FOR PREPARING POLY(γ-BUTYROLACTONE) WITH HIGH MOLECULAR WEIGHT | 青岛科技大学 | 2020-04-30 | — | — | WO | disclosed |
| CN-110804163-A | Preparation method of bio-based copolyester containing modifiable functional group | 青岛科技大学 | 2020-02-18 | — | — | CN | disclosed |
| WO-2019149086-A1 | POLYETHER-B-POLY (γ-BUTYROLACTONE) BLOCK COPOLYMER AND PREPARATION METHOD THEREFOR | 青岛科技大学 | 2019-08-08 | — | — | WO | disclosed |
| US-20100173917-A1 | UREA DERIVATIVES AS ABL MODULATORS | AMBIT BIOSCIENCES CORPORATION | 2010-07-08 | — | — | US | disclosed |
| US-20100173917-A1 | UREA DERIVATIVES AS ABL MODULATORS | AMBIT BIOSCIENCES CORPORATION | 2010-07-08 | — | — | US | disclosed |
| US-7750160-B2 | Isoxazolyl urea derivatives as kinase modulators | AMBIT BIOSCIENCES CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| US-7750160-B2 | Isoxazolyl urea derivatives as kinase modulators | AMBIT BIOSCIENCES CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| US-20090048337-A1 | Modulation of anxiety through blockade of anandamide hydrolysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-02-19 | — | — | US | disclosed |
| US-20090048337-A1 | Modulation of anxiety through blockade of anandamide hydrolysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-02-19 | — | — | US | disclosed |
| US-20070117782-A1 | INHIBITORS OF EPOXIDE HYDROLASES FOR THE TREATMENT OF INFLAMMATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-05-24 | — | — | US | disclosed |
| US-20070117782-A1 | INHIBITORS OF EPOXIDE HYDROLASES FOR THE TREATMENT OF INFLAMMATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-05-24 | — | — | US | disclosed |
| US-7176201-B2 | Modulation of anxiety through blockade of anandamide hydrolysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-13 | — | — | US | disclosed |
| US-7176201-B2 | Modulation of anxiety through blockade of anandamide hydrolysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048337-A1 | Modulation of anxiety through blockade of anandamide hydrolysis | FAAH, FAAH2, CNR2 | EPHX1 27/4885RAB9A 870/4885NPC1 625/4885 |
| US-20100173917-A1 | UREA DERIVATIVES AS ABL MODULATORS | ABL1, ABL2, BCR | EPHX1 2857/4885RAB9A 1325/4885NPC1 1569/4885 |
| US-20070117782-A1 | INHIBITORS OF EPOXIDE HYDROLASES FOR THE TREATMENT OF INFLAMMATION | EPHX1, LTA4H, PTGS1 | EPHX1 1/4885RAB9A 3871/4885NPC1 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.