Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089390 | 0.91 | AKR1C3 (0.35) | CYP1A2CYP2C19AKR1C3AKR1C2HSP90AA1 | |
| SCHEMBL10089349 | 0.89 | AKR1C3 (0.34) | CYP1A2CYP2C19AKR1C3AKR1C2HSP90AA1 | |
| SCHEMBL10089371 | 0.86 | CYP1A2 (0.39) | CYP1A2CYP2C19CYP2C9HSP90AA1HSP90AB1 | |
| SCHEMBL10089343 | 0.83 | EGFR (0.37) | CYP1A2CYP2C19CYP2C9HSP90AA1HSP90AB1 | |
| SCHEMBL10089347 | 0.81 | HIF1A (0.37) | CYP1A2CYP2C19CYP2C9HSP90AA1CYP2D6 | |
| SCHEMBL14703062 | 0.80 | CYP2D6 (0.36) | CYP1A2CYP2C19CYP2C9AKR1C3AKR1C2 | |
| SCHEMBL2331853 | 0.80 | CYP2D6 (0.38) | CYP1A2CYP2C19CYP2C9CYP2D6NR1I2 | |
| SCHEMBL10089361 | 0.78 | HIF1A (0.39) | CYP1A2CYP2C19CYP2C9HSP90AA1CYP2D6 | |
| SCHEMBL12445186 | 0.78 | EGFR (0.36) | CYP1A2CYP2C19CYP2C9CYP2D6NR1I2 | |
| SCHEMBL14702263 | 0.78 | CYP2D6 (0.36) | CYP1A2CYP2C19CYP2C9HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383753-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-02-26 | — | — | US | disclosed |
| US-8383753-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-02-26 | — | — | US | disclosed |
| US-20120029159-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120029159-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-02 | — | — | US | disclosed |
| US-8071701-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071701-B2 | Polydentate heteroatom ligand containing metal complexes, catalysts and methods of making and using the same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090221770-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES INC. | 2009-09-03 | — | — | US | disclosed |
| US-20090221770-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES INC. | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221770-A1 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | PICALM, PARG, POLM | CYP1A2 4502/4885CYP2C19 4184/4885CYP2C9 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.