Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089343 | 0.94 | EGFR (0.37) | EGFRERBB2AKR1B1CYP2D6LMNA | |
| SCHEMBL10089361 | 0.89 | HIF1A (0.39) | EGFRERBB2AKR1B1CYP2D6LMNA | |
| SCHEMBL14471345 | 0.84 | EGFR (0.34) | EGFRERBB2CYP2D6LMNANR1I2 | |
| SCHEMBL10089371 | 0.83 | CYP1A2 (0.39) | CYP2D6LMNANR1I2ADRA2AACHE | |
| SCHEMBL14471347 | 0.82 | CYP2D6 (0.35) | CYP2D6HIF1ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL2331853 | 0.81 | CYP2D6 (0.38) | CYP2D6LMNANR1I2ADRA2AACHE | |
| SCHEMBL10089349 | 0.81 | AKR1C3 (0.34) | CYP2D6LMNANR1I2ADRA2AACHE | |
| SCHEMBL10089355 | 0.80 | GPR84 (0.38) | EGFRERBB2CYP2D6LMNANR1I2 | |
| SCHEMBL10089390 | 0.80 | AKR1C3 (0.35) | CYP2D6LMNANR1I2ADRA2AACHE | |
| SCHEMBL12445306 | 0.80 | DHFR (0.35) | EGFRERBB2AKR1B1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2359930-A1 | A polymer prepared in the presence of metal complexes bearing a polydentate heteroatom ligand | Dow Global Technologies LLC (US) | 2011-08-24 | — | — | EP | disclosed |