Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.38 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 9/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089977 | 0.95 | KCNA5 (0.36) | ABCB1KCNB1ROCK2ROCK1PPARG | |
| SCHEMBL10090044 | 0.94 | PDE2A (0.35) | RIPK1PPARG | |
| SCHEMBL10090032 | 0.93 | GPR6 (0.36) | ABCB1RIPK1KCNB1GLSROCK2 | |
| SCHEMBL10089944 | 0.92 | RIPK1 (0.38) | ABCB1RIPK1KCNB1GLSMCL1 | |
| SCHEMBL10089909 | 0.89 | PPARG (0.36) | GLSPPARG | |
| SCHEMBL10089916 | 0.89 | KCNB1 (0.36) | ABCB1RIPK1KCNB1MCL1ROCK2 | |
| SCHEMBL10089987 | 0.89 | HSD17B13 (0.39) | RIPK1 | |
| SCHEMBL10089881 | 0.88 | GPR6 (0.36) | KCNB1GLSPPARG | |
| SCHEMBL10089991 | 0.87 | GPR6 (0.36) | — | |
| SCHEMBL10090019 | 0.86 | RIPK1 (0.38) | ABCB1RIPK1KCNB1GLSROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791143-B2 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2014-07-29 | — | — | US | disclosed |
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | DDT, ADCY1, ANTXR2 | ABCB1 3201/4885RIPK1 4585/4885KCNB1 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.