Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089896 | 0.93 | P2RX7 (0.38) | P2RX7KLKB1PPARGNTRK1MAPK8 | |
| SCHEMBL10089873 | 0.93 | MAPK8 (0.36) | P2RX7KLKB1NTRK1MAPK8TP53 | |
| SCHEMBL10089939 | 0.93 | P2RX7 (0.33) | P2RX7KLKB1PPARGNTRK1MAPK8 | |
| SCHEMBL10089973 | 0.92 | P2RX7 (0.36) | P2RX7TP53 | |
| SCHEMBL10089841 | 0.92 | TP53 (0.38) | P2RX7MAPK8TP53 | |
| SCHEMBL10089948 | 0.92 | TP53 (0.35) | P2RX7PPARGNTRK1MAPK8TP53 | |
| SCHEMBL10089867 | 0.91 | TP53 (0.33) | P2RX7KLKB1NTRK1TRPV1TP53 | |
| SCHEMBL10089888 | 0.91 | TP53 (0.34) | P2RX7KLKB1TRPV1TP53 | |
| SCHEMBL10089883 | 0.90 | P2RX7 (0.36) | P2RX7PPARGNTRK1TP53 | |
| SCHEMBL10089870 | 0.90 | KMT2A (0.36) | KLKB1PPARGNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791143-B2 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2014-07-29 | — | — | US | disclosed |
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | DDT, ADCY1, ANTXR2 | P2RX7 1165/4885KLKB1 4458/4885PPARG 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.