Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089867 | 0.95 | TP53 (0.33) | P2RX7EPHX2TP53HPGD | |
| SCHEMBL10089841 | 0.95 | TP53 (0.38) | P2RX7TSHRTP53HPGD | |
| SCHEMBL10089948 | 0.93 | TP53 (0.35) | P2RX7TP53 | |
| SCHEMBL10089925 | 0.92 | P2RX7 (0.35) | P2RX7TP53 | |
| SCHEMBL10089888 | 0.92 | TP53 (0.34) | P2RX7TP53 | |
| SCHEMBL10089896 | 0.92 | P2RX7 (0.38) | P2RX7 | |
| SCHEMBL10089883 | 0.92 | P2RX7 (0.36) | P2RX7EPHX2TP53HPGD | |
| SCHEMBL10089873 | 0.92 | MAPK8 (0.36) | P2RX7TP53 | |
| SCHEMBL10090013 | 0.92 | KLKB1 (0.40) | P2RX7HPGD | |
| SCHEMBL10089870 | 0.91 | KMT2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791143-B2 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2014-07-29 | — | — | US | disclosed |
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | DDT, ADCY1, ANTXR2 | P2RX7 1165/4885EPHX2 1227/4885TSHR 1267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.