SCHEMBL10089935

SCHEMBL10089935

Cc1cc(C#N)cc(C(=O)NCc2ccc(OC(F)F)cc2)c1NC(=O)c1cc(Cn2nnc(C(F)(F)F)n2)nn1-c1c(Cl)cccc1Cl

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 9/20 0.36
SLC2A3 P11169 9/20 0.36
SLC2A4 P14672 9/20 0.36
NR1I2 O75469 1/20 0.35
PPARG P37231 1/20 0.35
ELANE P08246 2/20 0.35
CPT1A P50416 2/20 0.34
CPT1B Q92523 2/20 0.34
SLC2A2 P11168 3/20 0.34
GPR6 P46095 1/20 0.33
MMP13 P45452 2/20 0.32
USP36 Q9P275 1/20 0.32
CNR2 P34972 1/20 0.32
LMNA P02545 1/20 0.32
CPT2 P23786 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10089945 0.95 KLKB1 (0.35) SLC2A1SLC2A3SLC2A4PPARGELANE
SCHEMBL10089980 0.94 IDH1 (0.36) SLC2A1SLC2A3SLC2A4NR1I2PPARG
SCHEMBL10089859 0.93 SLC2A1 (0.37) SLC2A1SLC2A3SLC2A4ELANESLC2A2
SCHEMBL10089975 0.92 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4NR1I2PPARG
SCHEMBL10090041 0.90 GPR6 (0.34) SLC2A1SLC2A3SLC2A4GPR6
SCHEMBL10089953 0.90 RIPK1 (0.37) SLC2A1SLC2A3SLC2A4PPARG
SCHEMBL10089908 0.89 KLKB1 (0.35) SLC2A1SLC2A3SLC2A4PPARGELANE
SCHEMBL10090042 0.88 GPR6 (0.35) SLC2A1SLC2A3SLC2A4ELANESLC2A2
SCHEMBL13085225 0.87 SLC2A1 (0.37) SLC2A1SLC2A3SLC2A4ELANESLC2A2
SCHEMBL10089857 0.87 LMNA (0.39) SLC2A1SLC2A3SLC2A4SLC2A2MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8791143-B2 Anthranilic diamide derivatives having cyclic side-chains BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
US-20120010249-A1 Anthranilic diamide derivatives having cyclic side-chains BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010249-A1 Anthranilic diamide derivatives having cyclic side-chains DDT, ADCY1, ANTXR2 SLC2A1 3782/4885SLC2A3 3762/4885SLC2A4 3927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.