Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B13 | Q7Z5P4 | 3/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10090029 | 0.94 | HSD17B13 (0.40) | HSD17B13MAPK8RIPK1EPHX2 | |
| SCHEMBL10090045 | 0.90 | NR1I2 (0.36) | GPR6 | |
| SCHEMBL10089901 | 0.90 | MAPK8 (0.34) | HSD17B13MAPK8DHODHRIPK1EPHX2 | |
| SCHEMBL10089970 | 0.88 | GPR6 (0.36) | HSD17B13MAPK8DHODHEPHX2LIPG | |
| SCHEMBL13085130 | 0.87 | DHODH (0.33) | DHODH | |
| SCHEMBL13084847 | 0.87 | DHODH (0.32) | DHODH | |
| SCHEMBL10089995 | 0.86 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL10090003 | 0.86 | PDE2A (0.34) | RIPK1EPHX2MAPK1 | |
| SCHEMBL13085200 | 0.85 | DHODH (0.33) | DHODH | |
| SCHEMBL10089844 | 0.85 | MAPK8 (0.35) | HSD17B13MAPK8DHODHEPHX2LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582695-B1 | ANTHRANILIC ACID DIAMIDE DERIVATIVES WITH CYCLICAL SIDE CHAINS | BAYER IP GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-8791143-B2 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2014-07-29 | — | — | US | disclosed |
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | DDT, ADCY1, ANTXR2 | HSD17B13 4352/4885MAPK8 4028/4885DHODH 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.