Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9666845 | 0.98 | ACHE (0.48) | ACHEGDAABL1RIN1ADORA2B | |
| Water SCHEMBL9462016 | 0.98 | ACHE (0.48) | ACHEGDAABL1RIN1ADORA2B | |
| Hydrochloric Acid SCHEMBL9461578 | 0.96 | ACHE (0.47) | ACHEGDAABL1RIN1ADORA2B | |
| Water SCHEMBL9461623 | 0.96 | ACHE (0.47) | ACHEGDAABL1RIN1ADORA2B | |
| SCHEMBL1898184 | 0.78 | GDA (0.48) | ACHEGDAABL1RIN1ADORA2B | |
| Guanine SCHEMBL342789 | 0.78 | ADORA3 (0.62) | ACHEGDAABL1RIN1ADORA2B | |
| SCHEMBL6429381 | 0.78 | GDA (0.48) | ACHEGDAABL1RIN1ADORA2B | |
| SCHEMBL8230116 | 0.78 | ACHE (0.48) | ACHEGDAABL1RIN1ADORA2B | |
| SCHEMBL612212 | 0.78 | ACHE (0.48) | ACHEGDAABL1RIN1ADORA2B | |
| SCHEMBL8663355 | 0.76 | GDA (0.46) | ACHEGDAABL1RIN1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466164-B1 | Process for the preparation of 2-chloro-1,7-dihydropurin-6-one and process for the purification of the same | BOEHRINGER INGELHEIM KG (DE) | 1995-06-07 | — | — | EP | claimed |
| US-5264573-A | Process for preparing 2-chloro-1,7-dihydropurin-6-one and a process for its purification | BOEHRINGER INGELHEIM GMBH (DE) | 1993-11-23 | — | — | US | claimed |
| JP-4230383-A | — | — | None | — | — | JP | disclosed |
| CN-121721172-A | Solid phase extraction-vacuum centrifugal concentration-liquid chromatography tandem mass spectrometry detection method for chloro-product of flavor nucleotide | 浙江大学 | 2026-03-24 | — | — | CN | disclosed |
| EP-2268607-B9 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2015-05-13 | — | — | EP | disclosed |
| EP-2268607-B1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2015-02-18 | — | — | EP | disclosed |
| US-8895734-B2 | Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid | OLIPASS CORPORATION (KR) | 2014-11-25 | — | — | US | disclosed |
| US-8884008-B2 | Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid | OLIPASS CORPORATION (KR) | 2014-11-11 | — | — | US | disclosed |
| US-20140323728-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2014-10-30 | — | — | US | disclosed |
| US-8859766-B2 | Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid | OLIPASS CORPORATION (KR) | 2014-10-14 | — | — | US | disclosed |
| US-20140155605-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2014-06-05 | — | — | US | disclosed |
| WO-2009113828-A2 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2009-09-17 | — | — | WO | disclosed |
| US-5658731-A | GENE EXPRESSION; COMPLEXING REACTIONS | EUROPAISCHES LABORATORIUM FUR MOLEKULARBIOLOGIE (DE) | 1997-08-19 | — | — | US | disclosed |
| US-5264573-A | Process for preparing 2-chloro-1,7-dihydropurin-6-one and a process for its purification | BOEHRINGER INGELHEIM GMBH (DE) | 1993-11-23 | — | — | US | disclosed |
| JP-H04230383-A | PRODUCTION OF 2-CHLORO-1,7-DIHYDRO PURIN-6-ONE, AND ITS PURIFICATION | BOEHRINGER INGELHEIM KG | 1992-08-19 | — | — | JP | disclosed |
| US-4663446-A | BACTERICIDES, POLYMERASE INHIBITORS | TRUSTEES OF THE UNIV. OF MASSACHUSETTS (US) | 1987-05-05 | — | — | US | disclosed |
| US-4602089-A | Process for preparing purine compounds | NEWPORT PHARMACEUTICALS, INC. (US) | 1986-07-22 | — | — | US | disclosed |
| EP-0126813-A1 | Process for preparing imidazole compounds | Newport Pharmaceuticals International, Inc. (US) | 1984-12-05 | — | — | EP | disclosed |
| US-4451478-A | IMMUNOLOGY, ACTIVATORS | NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 1984-05-29 | — | — | US | disclosed |
| US-4371613-A | TRANSARABINOSYLATION USING AN ENZYME FROM BACTERIA, AN ARABINOSE DONOR AND A PURINE SOURCE | AJINOMOTO COMPANY INCORPORATED (JP) | 1983-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323728-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | SLC7A1, SLC29A1, SLC43A3 | ACHE 4861/4885GDA 508/4885ABL1 2910/4885 |
| US-20140155605-A1 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | SLC7A1, SLC29A1, SLC43A3 | ACHE 4861/4885GDA 508/4885ABL1 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.