SCHEMBL6429381

SCHEMBL6429381

O=c1nc(S)[nH]c2nc[nH]c12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.48
ACHE P22303 1/20 0.48
ABL1 P00519 1/20 0.44
RIN1 Q13671 1/20 0.44
ADORA2B P29275 7/20 0.43
ADORA2A P29274 4/20 0.43
ADORA3 P0DMS8 7/20 0.41
ALDH1A1 P00352 3/20 0.41
TP53 P04637 2/20 0.41
HPGD P15428 2/20 0.41
PTGS1 P23219 2/20 0.41
HBB P68871 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
USP2 O75604 1/20 0.41
MAPK3 P27361 1/20 0.41
XDH P47989 1/20 0.41
PAX8 Q06710 1/20 0.41
PDE4A P27815 3/20 0.40
PDE4B Q07343 3/20 0.40
PDE4C Q08493 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1009012 0.78 ACHE (0.50) GDAACHEABL1RIN1ADORA2B
Hydrochloric Acid SCHEMBL9666845 0.77 ACHE (0.48) GDAACHEABL1RIN1ADORA2B
Water SCHEMBL9462016 0.77 ACHE (0.48) GDAACHEABL1RIN1ADORA2B
Guanine SCHEMBL342789 0.77 ADORA3 (0.62) GDAACHEABL1RIN1ADORA2B
SCHEMBL1898184 0.77 GDA (0.48) GDAACHEABL1RIN1ADORA2B
SCHEMBL8230116 0.77 ACHE (0.48) GDAACHEABL1RIN1ADORA2B
SCHEMBL612212 0.77 ACHE (0.48) GDAACHEABL1RIN1ADORA2B
Water SCHEMBL9461623 0.76 ACHE (0.47) GDAACHEABL1RIN1ADORA2B
Hydrochloric Acid SCHEMBL9461578 0.76 ACHE (0.47) GDAACHEABL1RIN1ADORA2B
SCHEMBL8663355 0.74 GDA (0.46) GDAACHEABL1RIN1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447746-A Compound for activating AMPK and application thereof HUAAN MEDICAL CO LTD 2015-03-25 CN claimed
US-5792793-A STABLE COMPLEX COMPRISING SILVER AND A THIOL COMPOUND; NONIRRITATING TO SKIN/MUCOUS MEMBRANES AND COMPATIBLE WITH CARRIER RESINS MEIJI MILK PRODUCTS CO., LTD. (JP) 1998-08-11 US claimed
CN-106460217-B Multilayer coating film and article having the same 奥野制药工业株式会社 2021-05-04 CN disclosed
EP-3159436-B1 ARTICLE HAVING MULTILAYER PLATING FILM OKUNO CHEM IND CO (JP) 2019-11-20 EP disclosed
US-20170114470-A1 MULTILAYER PLATING FILM AND ARTICLE HAVING MULTILAYER PLATING FILM OKUNO CHEMICAL INDUSTRIES CO., LTD. (JP) 2017-04-27 US disclosed
EP-3159436-A1 MULTILAYER PLATING FILM AND ARTICLE HAVING MULTILAYER PLATING FILM Okuno Chemical Industries Co., Ltd. (JP) 2017-04-26 EP disclosed
CN-104447746-A Compound for activating AMPK and application thereof HUAAN MEDICAL CO LTD 2015-03-25 CN disclosed
EP-1107056-B1 Method of processing a silver halide photographic light sensitive material KONISHIROKU PHOTO IND (JP) 2005-05-11 EP disclosed
EP-0774687-B1 Solid processing composition and method for processing silver halide photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 2004-09-15 EP disclosed
US-6740478-B2 Method for processing silver halide light-sensitive photographic material KONICA CORPORATION (JP) 2004-05-25 US disclosed
US-6653060-B2 Triether derivative developer, fixer of thiosulfate salts, water-soluble aluminum salts, and crystallization retarding agents; staining of water washing tank and processing unevenness are minimized using automatic processing machines KONICA CORPORATION (JP) 2003-11-25 US disclosed
EP-0754966-A1 Silver halide light-sensitive photographic material and processing method thereof KONICA CORPORATION (JP) 1997-01-22 EP disclosed
EP-0727427-A1 ANTIBACTERIAL, ANTIFUNGAL AND ANTIVIRAL AGENT MEIJI MILK PRODUCTS COMPANY LIMITED (JP) 1996-08-21 EP disclosed
EP-0696759-A2 Method for processing a silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1996-02-14 EP disclosed
EP-0676667-A1 Method of processing photographic light-sensitive material KONICA CORPORATION (JP) 1995-10-11 EP disclosed
EP-0647880-A1 Method of processing silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1995-04-12 EP disclosed
EP-0073490-B1 DIHYDROTHIAZOLE-PURINES Newport Pharmaceuticals International, Inc. (US) 1986-04-30 EP disclosed
US-4510144-A Methods of imparting immunomodulating activity with dihydrothiazolo purine derivatives NEWPORT PHARMACEUTICALS INTERNATIONAL (US) 1985-04-09 US disclosed
US-4387226-A VIRICIDES, IMMUNOLOGY NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) 1983-06-07 US disclosed
EP-0073490-A1 Dihydrothiazole-purines Newport Pharmaceuticals International, Inc. (US) 1983-03-09 EP disclosed