Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10065550 | 0.88 | HTR1A (0.40) | HTR1ACYP19A1HTR2AHTR2CKDM1A | |
| SCHEMBL27085532 | 0.77 | — | — | |
| SCHEMBL27085525 | 0.75 | CYP19A1 (0.42) | CYP19A1DPP4ATP4AATP4B | |
| SCHEMBL628307 | 0.75 | TBXAS1 (0.42) | CYP19A1ALDH1A1LMNAMAPTSMPD1 | |
| SCHEMBL11361006 | 0.75 | CYP19A1 (0.48) | CYP19A1ALDH1A1KMT2ADPP4 | |
| SCHEMBL6071635 | 0.74 | — | — | |
| SCHEMBL11204798 | 0.73 | TBXAS1 (0.46) | CYP19A1LMNAMAPTSMPD1KDM4E | |
| SCHEMBL243704 | 0.73 | TBXAS1 (0.46) | CYP19A1LMNAMAPTSMPD1KDM4E | |
| SCHEMBL21925549 | 0.73 | TBXAS1 (0.46) | CYP19A1LMNAMAPTSMPD1KDM4E | |
| SCHEMBL3302887 | 0.73 | TBXAS1 (0.46) | CYP19A1LMNAMAPTSMPD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160152814-A1 | 4- AND 5-SUBSTITUTED 1,2,3-TRIAZOLE, AND REGIOISOMER MIXTURES THEREOF, MODIFIED POLYMERS | ISP INVESTMENTS INC. (US) | 2016-06-02 | — | — | US | disclosed |
| US-20160152814-A1 | 4- AND 5-SUBSTITUTED 1,2,3-TRIAZOLE, AND REGIOISOMER MIXTURES THEREOF, MODIFIED POLYMERS | ISP INVESTMENTS INC. (US) | 2016-06-02 | — | — | US | disclosed |
| US-9334351-B2 | 4- and 5-substituted 1,2,3-triazole, and regioisomer mixtures thereof, modified polymers | ISP INVESTMENTS INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-9334351-B2 | 4- and 5-substituted 1,2,3-triazole, and regioisomer mixtures thereof, modified polymers | ISP INVESTMENTS INC. (US) | 2016-05-10 | — | — | US | disclosed |
| US-8993698-B2 | 4- and 5 substituted 1,2,3-triazole moieties with at least one remote polymerizable moiety and polymers thereof | ISP INVESTMENTS INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-8993698-B2 | 4- and 5 substituted 1,2,3-triazole moieties with at least one remote polymerizable moiety and polymers thereof | ISP INVESTMENTS INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20140128550-A1 | 4- AND 5-SUBSTITUTED 1,2,3-TRIAZOLE, AND REGIOISOMER MIXTURES THEREOF, MODIFIED POLYMERS | ISP INVESTMENTS INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-20140128550-A1 | 4- AND 5-SUBSTITUTED 1,2,3-TRIAZOLE, AND REGIOISOMER MIXTURES THEREOF, MODIFIED POLYMERS | ISP INVESTMENTS INC. (US) | 2014-05-08 | — | — | US | disclosed |
| WO-2012174400-A1 | 4-AND 5-SUBSTITUTED 1,2,3-TRIAZOLE AND REGIOISOMER MIXTURES THEREOF, MODIFIED POLYMERS | ISP INVESTMENTS INC. (US) | 2012-12-20 | — | — | WO | disclosed |
| US-20120142846-A1 | 4- AND 5 SUBSTITUTED 1,2,3-TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | AVOCA LLC | 2012-06-07 | — | — | US | disclosed |
| US-20120142846-A1 | 4- AND 5 SUBSTITUTED 1,2,3-TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | AVOCA LLC | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152814-A1 | 4- AND 5-SUBSTITUTED 1,2,3-TRIAZOLE, AND REGIOISOMER MIXTURES THEREOF, MODIFIED POLYMERS | MGAT3, MYOC, MLEC | HTR1A 2391/4885CYP2D6 1080/4885CYP19A1 2794/4885 |
| US-20120142846-A1 | 4- AND 5 SUBSTITUTED 1,2,3-TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | H1-4, NPY4R, RXFP4 | HTR1A 860/4885CYP2D6 2615/4885CYP19A1 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.