SCHEMBL10092191

SCHEMBL10092191

c1ccc(-n2c3ccccc3c3ccccc32)c(-c2cccc3c2oc2c(-c4ccccc4-n4c5ccccc5c5ccccc54)cc(-n4c5ccccc5c5ccccc54)cc23)c1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 2/20 0.35
ALOX5 P09917 2/20 0.34
DUSP3 P51452 1/20 0.31
PRKDC P78527 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
TSHR P16473 1/20 0.30
BRCA1 P38398 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24041288 0.88 ALOX5 (0.39) KDM4EATML3MBTL1ALDH1A1ALOX5
SCHEMBL26536780 0.84 ALOX5 (0.50) KDM4EATML3MBTL1ALDH1A1ALOX5
SCHEMBL5030179 0.84 ALOX5 (0.36) KDM4EATML3MBTL1ALDH1A1ALOX5
SCHEMBL5028292 0.84 ALOX5 (0.41) KDM4EATML3MBTL1ALDH1A1ALOX5
SCHEMBL21147966 0.83 ALOX5 (0.46) KDM4EATML3MBTL1ALDH1A1ALOX5
SCHEMBL10038503 0.82 KDM4E (0.43) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL24067180 0.82 ALOX5 (0.45) KDM4EATML3MBTL1ALDH1A1ALOX5
SCHEMBL21583628 0.81 ALOX5 (0.49) KDM4EATML3MBTL1ALDH1A1ALOX5
SCHEMBL10092195 0.80 ALOX5 (0.46) KDM4EATML3MBTL1ALDH1A1ALOX5
SCHEMBL20412455 0.80 ALOX5 (0.50) KDM4EATML3MBTL1ALDH1A1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130119360-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME MERCK PATENT GMBH (DE) 2013-05-16 US disclosed
US-8367224-B2 Organic electroluminescence element, new compound for the same, display device and lighting device using the same KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-05 US disclosed
EP-2453496-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta Holdings, Inc. (JP) 2012-05-16 EP disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME AOC2, AOC3, CDYL KDM4E 367/4885ATM 3194/4885L3MBTL1 1475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.