SCHEMBL1009292

SCHEMBL1009292

COC(=O)c1nccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28652061 0.98 ALDH1A1 (0.59)
SCHEMBL9568835 0.79
SCHEMBL9568970 0.79
SCHEMBL20746452 0.79
SCHEMBL9568892 0.79
SCHEMBL6972528 0.79
SCHEMBL17201513 0.79 ALDH1A1 (0.55)
SCHEMBL12124477 0.79 ALDH1A1 (0.55)
SCHEMBL837325 0.79 ALDH1A1 (0.55)
SCHEMBL2800676 0.77 ALDH1A1 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118116485-A Reaction risk assessment method of continuous fluidized bed 浙江化安安全技术研究院有限公司 2024-05-31 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-102985420-A Cytochrome P450 inhibitors and uses thereof ANGION BIOMEDICA CORP 2013-03-20 CN claimed
CN-1738805-A N- (1-benzyl-2-oxo-2- (1-piperazinyl) ethyl) -1-piperidincarboxamid-derivatives and related compounds use as CGRP-antagonists for treating a headache BOEHRINGER INGELHEIM INT (DE) 2006-02-22 CN claimed
EP-4746963-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
WO-2026103337-A1 NOVEL SUBSTITUTED HETEROCYCLIC COMPOUND AS APELIN RECEPTOR MODULATOR 德睿智药(苏州)新药研发有限公司 2026-05-21 WO disclosed
WO-2026101959-A1 HETEROAROMATIC INDOLESULFONAMIDES SEED THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
EP-4713306-A1 NOVEL TRACER FOR THE IN VIVO DETECTION OF THE AGGREGATION OF ALPHA-SYNUCLEIN Stichting Amsterdam UMC (NL) 2026-03-25 EP disclosed
US-20250179061-A1 RIP1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2025-06-05 US disclosed
WO-2025017045-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. HOFFMANN-LA ROCHE AG (CH) 2025-01-23 WO disclosed
WO-2024236054-A1 NOVEL TRACER FOR THE IN VIVO DETECTION OF THE AGGREGATION OF ALPHA-SYNUCLEIN Stichting Amsterdam UMC (NL) 2024-11-21 WO disclosed
CN-1382140-A Neurotrophic pyrrolidines and piperidines and related compositions containing them ORTHO MCNEIL PHARM INC (US) 2002-11-27 CN disclosed
EP-1219607-A1 INTEGRASE INHIBITORS CONTAINING AROMATIC HETEROCYCLE DERIVATIVES SHIONOGI & CO., LTD. (JP) 2002-07-03 EP disclosed
EP-0991625-A2 INHIBITORS OF FACTOR XA WITH A NEUTRAL P1 SPECIFICITY GROUP THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 2000-04-12 EP disclosed
CN-1244193-A Novel amide derivatives and medicinal compositions thereof YAMANOUCHI PHARMA CO LTD (JP) 2000-02-09 CN disclosed
WO-1998057937-A2 INHIBITORS OF FACTOR XA WITH A NEUTRAL P1 SPECIFICITY GROUP THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1998-12-23 WO disclosed
US-4009164-A Novel 2-substituted-1,2,4-thiadiazole-[2,3-a]-benzimidazoles and process for their preparation SYNTEX (U.S.A.) INC. (US) 1977-02-22 US disclosed
US-3976654-A FUNGICIDE SYNTEX (U.S.A.) INC. (US) 1976-08-24 US disclosed
US-3946031-A FUNGICIDES SYNTEX INC. (US) 1976-03-23 US disclosed