Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RBBP9 | O75884 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29000634 | 0.98 | ALDH1A1 (0.53) | ALDH1A1PKMMAPTHTTLMNA | |
| Hydrochloric Acid SCHEMBL14763613 | 0.98 | ALDH1A1 (0.53) | ALDH1A1PKMMAPTHTTLMNA | |
| Piperazine SCHEMBL27525909 | 0.91 | ALDH1A1 (0.46) | ALDH1A1PKMMAPTHTTLMNA | |
| SCHEMBL25242978 | 0.83 | ALDH1A1 (0.57) | ALDH1A1PKMMAPTHTTLMNA | |
| SCHEMBL25243570 | 0.83 | ALDH1A1 (0.52) | ALDH1A1PKMMAPTHTTLMNA | |
| SCHEMBL27647394 | 0.83 | L3MBTL1 (0.58) | ALDH1A1PKMLMNAHSD17B10MAPK1 | |
| SCHEMBL3219037 | 0.82 | ALDH1A1 (0.58) | ALDH1A1PKMMAPTHTTLMNA | |
| Ethyl Acetate SCHEMBL15874941 | 0.81 | ALDH1A1 (0.70) | ALDH1A1PKMMAPTHTTLMNA | |
| SCHEMBL27444649 | 0.80 | L3MBTL1 (0.52) | ALDH1A1MAPTLMNARAB9AKDM4E | |
| SCHEMBL1489443 | 0.80 | ALDH1A1 (0.51) | ALDH1A1PKMMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-218339475-U | Extraction device of thiazole carboxylic acid ethyl ester | 安徽勇晟医药科技有限公司 | 2023-01-20 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| CN-105924406-B | A kind of preparation method of acotiamide hydrochloride trihydrate | 河北国龙制药有限公司 | 2018-04-10 | — | — | CN | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| CN-102388027-B | Isothiazolyloxyphenylamidines and their use as fungicides | BAYER CROPSCIENCE AG | 2015-07-01 | — | — | CN | claimed |
| CN-103788084-A | Tetrahydroisoquinoline derivative and synthesis method thereof | Hunan huateng pharmaceutical co ltd | 2014-05-14 | — | — | CN | claimed |
| JP-9188670-A | — | — | None | — | — | JP | disclosed |
| US-20250188094-A1 | PYRAZOLE MEMBRANE-ASSOCIATED TYROSINE-AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (PKMYT1) INHIBITORS AND USES THEREOF | INSILICO MEDICINE LTD. (CN) | 2025-06-12 | — | — | US | disclosed |
| EP-4493557-A1 | PYRAZOLE MEMBRANE-ASSOCIATED TYROSINE-AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (PKMYT1) INHIBITORS AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2025-01-22 | — | — | EP | disclosed |
| CN-119192103-A | Five-membered heterocyclic amide compound, preparation method and application thereof, and bactericide | 贵州大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-119053592-A | Pyrazole membrane-associated tyrosine and threonine specific CDC2 inhibitor kinase (PKMYT 1) inhibitors and uses thereof | 英矽智能科技知识产权有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-118339274-A | Brandy replica | 艾娃食品实验室股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-117374383-A | Eutectic solid electrolyte for lithium metal battery and preparation method and application thereof | 南开大学 | 2024-01-09 | — | — | CN | disclosed |
| EP-0571471-B1 | 5-HETEROYL INDOLE DERIVATIVES | PFIZER (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5409941-A | 5-heteroyl indole derivatives | PFIZER INC. (US) | 1995-04-25 | — | — | US | disclosed |
| CN-1081675-A | By the new pyrethroid of thiazolic alcohol derivative, its preparation method and as the purposes of agricultural chemicals | ROUSSEL UCLAF (FR) | 1994-02-09 | — | — | CN | disclosed |
| EP-0571471-A1 | 5-HETEROYL INDOLE DERIVATIVES. | PFIZER (US) | 1993-12-01 | — | — | EP | disclosed |
| WO-1992013856-A1 | 5-HETEROYL INDOLE DERIVATIVES | PFIZER INC. (US) | 1992-08-20 | — | — | WO | disclosed |
| EP-0486948-A2 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1992-05-27 | — | — | EP | disclosed |
| CN-1048386-A | Novel thiazole base alkoxy acrylic ester, they the preparation method, do the purposes of mycocide and prepare the intermediate of this compounds | ROUSSEL UCLAF (FR) | 1991-01-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | ALDH1A1 4757/4885PKM 2108/4885MAPT 150/4885 |
| US-20250188094-A1 | PYRAZOLE MEMBRANE-ASSOCIATED TYROSINE-AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (PKMYT1) INHIBITORS AND USES THEREOF | PKMYT1, LMTK2, MAST1 | ALDH1A1 4768/4885PKM 73/4885MAPT 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.