SCHEMBL20746452

SCHEMBL20746452

NOC(=O)c1nccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8973785 0.80 ALDH1A1 (0.52)
SCHEMBL9568892 0.79
SCHEMBL6972528 0.79
SCHEMBL9568970 0.79
SCHEMBL1009292 0.79
SCHEMBL9568835 0.79
Hydrochloric Acid SCHEMBL28652061 0.78 ALDH1A1 (0.59)
SCHEMBL25242978 0.76 ALDH1A1 (0.57)
SCHEMBL25243570 0.76 ALDH1A1 (0.52)
SCHEMBL359025 0.76 ALDH1A1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11320376-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes ELITECHGROUP MDX LLC (US) 2022-05-03 US disclosed
US-20210041360-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2021-02-11 US disclosed
US-10890529-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes ELITECHGROUP, INC. (US) 2021-01-12 US disclosed
EP-3668884-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITechGroup Inc. (US) 2020-06-24 EP disclosed
US-10677728-B2 Duplex stabilizing fluorescence quenchers for nucleic acid probes ELITECHGROUP B.V. (NL) 2020-06-09 US disclosed
US-20200173924-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2020-06-04 US disclosed
WO-2019036225-A1 DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES ELITECHGROUP, INC. (US) 2019-02-21 WO disclosed