Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | APAF1 | O14727 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAD52 | P43351 | 3/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.56 |
| ▸ | FYN | P06241 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950044 | 0.91 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2LMNATSHR | |
| SCHEMBL10093501 | 0.85 | LMNA (0.50) | KMT2AMEN1SMN1; SMN2LMNATSHR | |
| SCHEMBL16326281 | 0.83 | TSHR (0.61) | KMT2AMEN1SMN1; SMN2LMNATSHR | |
| Hydrochloric Acid SCHEMBL426559 | 0.82 | TSHR (0.60) | KMT2AMEN1SMN1; SMN2LMNATSHR | |
| SCHEMBL17927915 | 0.82 | LMNA (0.46) | KMT2AMEN1SMN1; SMN2LMNATSHR | |
| SCHEMBL10093502 | 0.79 | LMNA (0.44) | KMT2AMEN1SMN1; SMN2LMNATSHR | |
| SCHEMBL26657537 | 0.76 | SMN1; SMN2 (0.67) | KMT2AMEN1SMN1; SMN2LMNATSHR | |
| SCHEMBL9269061 | 0.75 | NPC1 (0.51) | KMT2AMEN1LMNATSHRACHE | |
| SCHEMBL4288920 | 0.75 | SMN1; SMN2 (0.63) | KMT2AMEN1SMN1; SMN2LMNATSHR | |
| SCHEMBL171239 | 0.75 | SMN1; SMN2 (0.59) | KMT2AMEN1SMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101163-B2 | Transdermal compositions | MICRODERMIS CORPORATION (US) | 2012-01-24 | — | — | US | disclosed |
| US-7893285-B2 | Transdermal compositions | MICRODERMIS CORPORATION (US) | 2011-02-22 | — | — | US | disclosed |
| US-20100227929-A1 | TRANSDERMAL COMPOSITIONS | DRS. SOLUTIONS, LLC (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100203005-A1 | TRANSDERMAL COMPOSITIONS | DRS. SOLUTIONS, LLC (US) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100203005-A1 | TRANSDERMAL COMPOSITIONS | S100A10, TMSB10, FFAR3 | KMT2A 4309/4885MEN1 2596/4885SMN1; SMN2 4798/4885 |
| US-20100227929-A1 | TRANSDERMAL COMPOSITIONS | S100A10, TMSB10, FFAR3 | KMT2A 4309/4885MEN1 2596/4885SMN1; SMN2 4798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.