Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.98 |
| ▸ | CES1 | P23141 | 4/20 | 0.77 |
| ▸ | FAAH2 | Q6GMR7 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713167 | 0.99 | FAAH (1.00) | FAAHCES1FAAH2 | |
| SCHEMBL3196450 | 0.88 | FAAH (0.98) | FAAHCES1FAAH2 | |
| SCHEMBL10095119 | 0.88 | FAAH (0.77) | FAAHCES1FAAH2 | |
| SCHEMBL710374 | 0.87 | FAAH (0.83) | FAAHCES1FAAH2 | |
| SCHEMBL3203964 | 0.87 | FAAH (1.00) | FAAHCES1FAAH2 | |
| SCHEMBL3193713 | 0.87 | FAAH (1.00) | FAAHCES1FAAH2 | |
| SCHEMBL3183288 | 0.87 | FAAH (1.00) | FAAHCES1FAAH2 | |
| SCHEMBL1471932 | 0.87 | FAAH (1.00) | FAAHCES1FAAH2 | |
| SCHEMBL711256 | 0.87 | FAAH (0.78) | FAAHCES1FAAH2 | |
| SCHEMBL711231 | 0.87 | FAAH (0.78) | FAAHCES1FAAH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124778-B2 | Tricyclic inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100216750-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216750-A1 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FADS1, FAAH, SCD | FAAH 2/4885CES1 22/4885FAAH2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.