SCHEMBL1471932

SCHEMBL1471932

O=C(CCCCCCc1ccccc1)c1ncc(-c2ccccn2)o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 1.00
CES1 P23141 4/20 1.00
FAAH2 Q6GMR7 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3183288 1.00 FAAH (1.00) FAAHCES1FAAH2
SCHEMBL3203964 1.00 FAAH (1.00) FAAHCES1FAAH2
SCHEMBL3193713 1.00 FAAH (1.00) FAAHCES1FAAH2
SCHEMBL3196450 0.99 FAAH (0.98) FAAHCES1FAAH2
SCHEMBL3184217 0.95 FAAH (0.91) FAAHCES1FAAH2
SCHEMBL712398 0.92 FAAH (0.85) FAAHCES1FAAH2
SCHEMBL710374 0.91 FAAH (0.83) FAAHCES1FAAH2
SCHEMBL720053 0.91 FAAH (0.83) FAAHCES1FAAH2
SCHEMBL719614 0.91 FAAH (0.83) FAAHCES1FAAH2
SCHEMBL710756 0.91 FAAH (0.83) FAAHCES1FAAH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024225481-A1 AGENT FOR IMPROVING THERAPEUTIC RESPONSIVENESS IN CANCER IMMUNOTHERAPY WITH PD-1 INHIBITOR OR PD-L1 INHIBITOR 国立大学法人京都大学 2024-10-31 WO claimed
US-20260103492-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2026-04-16 US disclosed
EP-4665718-A1 SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF Apogee Pharmaceuticals, Inc. (CA) 2025-12-24 EP disclosed
US-12421281-B2 Cyclosporine compositions and methods of use BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-09-23 US disclosed
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof APOGEE PHARMACEUTICALS, INC. (CA) 2025-08-05 US disclosed
US-20250205175-A1 Anti-Aging Composition with mTOR inhibitor for Humans and Other Mammals POSTREL RICHARD (US) 2025-06-26 US disclosed
US-20250179121-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-06-05 US disclosed
US-20250152562-A1 Compositions to Enhance and Extend Quality of Life POSTREL RICHARD (US) 2025-05-15 US disclosed
WO-2025085674-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF ULCERATIVE COLITIS BACAINN THERAPEUTICS, INC. (US) 2025-04-24 WO disclosed
US-12280019-B2 Anti-aging therapy for humans and other mammals POSTREL RICHARD (US) 2025-04-22 US disclosed
WO-2007098142-A2 OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 2007-08-30 WO disclosed
WO-2007098142-A2 OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 2007-08-30 WO disclosed
WO-2007061862-A2 2-KETO-OXAZOLES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA N.V. (BE) 2007-05-31 WO disclosed
WO-2007005510-A1 N-HETEROARYLPIPERAZINYL UREAS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA N.V. (BE) 2007-01-11 WO disclosed
US-20070004741-A1 N-heteroarylpiperazinyl ureas as modulators of fatty acid amide hydrolase APODACA RICHARD 2007-01-04 US disclosed
US-20070004741-A1 N-heteroarylpiperazinyl ureas as modulators of fatty acid amide hydrolase APODACA RICHARD 2007-01-04 US disclosed
EP-1549624-A4 INHIBITORS OF FATTY ACID AMIDE HYDROLASE SCRIPPS RESEARCH INST (US) 2006-09-20 EP disclosed
US-20060111359-A1 enzyme inhibitor for treating sleep disorders THE SCRIPPS RESEARCH INSTITUTE (US) 2006-05-25 US disclosed
EP-1549624-A2 INHIBITORS OF FATTY ACID AMIDE HYDROLASE The Scripps Research Institute (US) 2005-07-06 EP disclosed
WO-2004033652-A2 INHIBITORS OF FATTY ACID AMIDE HYDROLASE THE SCRIPPS RESEARCH INSTITUTE (US) 2004-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103492-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE ABCC1, SLC47A2, ABCB1 FAAH 2184/4885CES1 1382/4885FAAH2 1345/4885
US-20060111359-A1 enzyme inhibitor for treating sleep disorders FAAH, FAAH2, HCRTR2 FAAH 1/4885CES1 12/4885FAAH2 2/4885
US-12421281-B2 Cyclosporine compositions and methods of use FPR2, FPR1, FPR3 FAAH 2000/4885CES1 940/4885FAAH2 898/4885
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof MGLL, PNLIP, LPL FAAH 12/4885CES1 46/4885FAAH2 23/4885
US-20250179121-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE FPR2, FPR1, FPR3 FAAH 1629/4885CES1 470/4885FAAH2 816/4885
US-20070004741-A1 N-heteroarylpiperazinyl ureas as modulators of fatty acid amide hydrolase FAAH, FAAH2, CNR2 FAAH 1/4885CES1 208/4885FAAH2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.