SCHEMBL1009635

SCHEMBL1009635

BrCCCCCCCOC1CCCCO1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
KDM4C Q9H3R0 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19173048 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL29125008 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL2744005 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL30954764 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL203262 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL19172281 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL23015072 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL1069647 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL2786532 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL1008189 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332112-A1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2025-10-30 US disclosed
EP-4574172-A2 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2025-06-25 EP disclosed
EP-4466250-B1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2025-03-26 EP disclosed
EP-4466250-A1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2024-11-27 EP disclosed
CN-118922401-A Ionizable cationic lipids for lipid nanoparticles 盖纳万科学有限公司 2024-11-08 CN disclosed
WO-2023144798-A1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2023-08-03 WO disclosed
WO-2023144798-A1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES GENEVANT SCIENCES GMBH (CH) 2023-08-03 WO disclosed
US-11365192-B2 Pyridine compound substituted with azole TAISHO PHARMACEUTICAL CO., LTD. (JP) 2022-06-21 US disclosed
US-11365183-B2 Eicosanoid derivatives MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (DE) 2022-06-21 US disclosed
US-20210122741-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE TAISHO PHARMACEUTICAL CO., LTD (JP) 2021-04-29 US disclosed
US-5114940-A Insecticides or anthelmintics from fused ring heterocycles containing amides or thioamides ROUSSEL-UCLAF (FR) 1992-05-19 US disclosed
EP-0317188-A2 Heteroaromatic enamide derivatives and their use as pesticides ROUSSEL UCLAF (FR) 1989-05-24 EP disclosed
EP-0282940-A2 A method for the preparation of a gamma-substituted (E)-2-alken-1-AL Shin-Etsu Chemical Co., Ltd. (JP) 1988-09-21 EP disclosed
EP-0228222-A2 Pesticidal dihalovinylalkenylamides THE WELLCOME FOUNDATION LIMITED (GB) 1987-07-08 EP disclosed
EP-0022634-B1 ACYLATED INDOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS AND DRUGS COMPRISING THEM TEIJIN LIMITED (JP) 1983-04-06 EP disclosed
US-4317905-A Preparation of compounds containing two conjugated double bonds cis-cis and cis-trans MONTEDISON S.P.A. (IT) 1982-03-02 US disclosed
EP-0022634-A1 Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them TEIJIN LIMITED (JP) 1981-01-21 EP disclosed
EP-0011169-A1 Process for the stereo-selective preparation of (E),(E)-diolefines HOECHST AKTIENGESELLSCHAFT (DE) 1980-05-28 EP disclosed
US-4089897-A Geminal prostaglandin analogs MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-05-16 US disclosed
US-4090019-A Geminal prostaglandin analogs MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210122741-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE CYP2C19, CYP4A11, CYP11B1 MEN1 1907/4885KMT2A 813/4885KDM4C 480/4885
US-11365192-B2 Pyridine compound substituted with azole CYP2C19, CYP4A11, CYP11B1 MEN1 1907/4885KMT2A 813/4885KDM4C 480/4885
US-11365183-B2 Eicosanoid derivatives FABP3, PTGER3, PTGES3 MEN1 4701/4885KMT2A 4627/4885KDM4C 4722/4885
US-20250332112-A1 IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES CETP, NPC1L1, ABCB4 MEN1 2023/4885KMT2A 2016/4885KDM4C 3018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.