SCHEMBL1069647

SCHEMBL1069647

BrCCCCCCCCCCCOC1CCCCO1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
KDM4C Q9H3R0 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19173048 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL29125008 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL2744005 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL30954764 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL203262 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL19172281 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL23015072 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL2786532 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL1008189 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL1009635 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902399-B2 Fatty acids analogous THIA MEDICA AS (NO) 2011-03-08 US claimed
US-12397058-B2 Metabolically stable prodrugs TSRL, INC. (US) 2025-08-26 US disclosed
US-20240368410-A1 SELECTIVE SELF-ASSEMBLED MONOLAYERS VIA SPIN-COATING METHOD FOR USE IN DSA MERCK PATENT GMBH (DE) 2024-11-07 US disclosed
US-12019075-B2 Zwitterionic nanoparticles FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) 2024-06-25 US disclosed
CN-117957209-A Selective self-assembled monolayers for DSA via spin coating 默克专利股份有限公司 2024-04-30 CN disclosed
CN-116496289-A Synthesis and application of membrane-targeted naphthalene endoperoxides 大连理工大学 2023-07-28 CN disclosed
US-20230160902-A1 ZWITTERIONIC NANOPARTICLES FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) 2023-05-25 US disclosed
US-20230160902-A1 ZWITTERIONIC NANOPARTICLES FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) 2023-05-25 US disclosed
US-20230160902-A1 ZWITTERIONIC NANOPARTICLES FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) 2023-05-25 US disclosed
US-11299572-B2 Block copolymer LG CHEM, LTD. 2022-04-12 US disclosed
EP-0595796-A1 METHOD OF TREATMENT OF ANDROGEN-RELATED DISEASES ENDORECHERCHE INC. (CA) 1994-05-11 EP disclosed
WO-1993010741-A2 SEX STEROID ACTIVITY INHIBITORS ENDORECHERCHE INC. (CA) 1993-06-10 WO disclosed
US-5204337-A Estrogen nucleus derivatives for use in inhibition of sex steroid activity ENDORECHERCHE INC. (CA) 1993-04-20 US disclosed
EP-0485392-A1 ANDROGEN DERIVATIVES FOR USE IN THE INHIBITION OF SEX STEROID ACTIVITY ENDORECHERCHE INC. (CA) 1992-05-20 EP disclosed
EP-0480950-A1 COMBINATION THERAPY FOR PROPHYLAXIS AND/OR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA ENDORECHERCHE INC. (CA) 1992-04-22 EP disclosed
WO-1991000731-A1 COMBINATION THERAPY FOR PROPHYLAXIS AND/OR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA ENDORECHERCHE INC. (CA) 1991-01-24 WO disclosed
WO-1991000733-A1 METHOD OF TREATMENT OF ANDROGEN-RELATED DISEASES ENDORECHERCHE INC. (CA) 1991-01-24 WO disclosed
WO-1991000732-A1 ANDROGEN DERIVATIVES FOR USE IN THE INHIBITION OF SEX STEROID ACTIVITY ENDORECHERCHE INC. (CA) 1991-01-24 WO disclosed
EP-0367576-A2 Estrogen nucleus derivatives for use in the inhibition of sex steroid activity ENDORECHERCHE INC. (CA) 1990-05-09 EP disclosed
US-4243660-A 11-HEXADECENYL AND 11-HEPTADECENYL ACETATE; SYNERGISTIC EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1981-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12019075-B2 Zwitterionic nanoparticles ANXA3, ANXA5, ANXA11 MEN1 462/4885KMT2A 3627/4885KDM4C 4315/4885
US-20230160902-A1 ZWITTERIONIC NANOPARTICLES ANXA3, ANXA5, ANXA11 MEN1 846/4885KMT2A 3703/4885KDM4C 3902/4885
US-12397058-B2 Metabolically stable prodrugs CES1, CES2, CYP2S1 MEN1 1968/4885KMT2A 3952/4885KDM4C 2044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.