SCHEMBL1008189

SCHEMBL1008189

BrCCCCCCCCCOC1CCCCO1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
KDM4C Q9H3R0 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19173048 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL29125008 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL2744005 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL30954764 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL203262 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL19172281 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL23015072 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL1069647 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL2786532 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL1009635 1.00 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12397058-B2 Metabolically stable prodrugs TSRL, INC. (US) 2025-08-26 US disclosed
WO-2025122011-A9 TRIGLYCERIDE ANALOGS ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) (NL) 2025-07-17 WO disclosed
WO-2025122011-A1 TRIGLYCERIDE ANALOGS ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) (NL) 2025-06-12 WO disclosed
EP-4561585-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS FOR USE IN THE TREATMENT, INHIBITION OF PROGRESSION, AND PREVENTION OF ECTOPIC CALCIFICATION Sanifit Therapeutics S.A. (ES) 2025-06-04 EP disclosed
CN-119855595-A IP4-4,6 substituted derivative compounds for treating ectopic calcification, inhibiting progression and preventing ectopic calcification 萨尼菲特治疗有限公司 2025-04-18 CN disclosed
US-20250011287-A1 FLUORINE-CONTAINING COMPOUND AND CONTRAST AGENT TDK CORPORATION (JP) 2025-01-09 US disclosed
CN-118613471-A Fluorochemical and contrast agent TDK株式会社 2024-09-06 CN disclosed
US-12060323-B2 6-hydroxy-3-hexenyl alkoxymethyl ether compound and a process for preparing a 3,13-octadecadien-1-ol compound from the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-08-13 US disclosed
US-20240109924-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS VIFOR (INTERNATIONAL) LTD. (CH) 2024-04-04 US disclosed
WO-2024023359-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS FOR USE IN THE TREATMENT, INHIBITION OF PROGRESSION, AND PREVENTION OF ECTOPIC CALCIFICATION SANIFIT THERAPEUTICS, S.A. (ES) 2024-02-01 WO disclosed
EP-2268606-A1 4-DIMETHYLAMINOBUTYRIC ACID DERIVATIVES F. Hoffmann-La Roche AG (CH) 2011-01-05 EP disclosed
WO-2009132978-A1 4-DIMETHYLAMINOBUTYRIC ACID DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2009-11-05 WO disclosed
US-20090270505-A1 4-DIMETHYLAMINOBUTYRIC ACID DERIVATIVES HOFFMANN-LA ROCHE, INC. 2009-10-29 US disclosed
WO-2008044033-A1 AMIDE DERIVATIVES ASTRAZENECA AB (SE) 2008-04-17 WO disclosed
EP-1803150-A1 COMPOUNDS FOR MYOCARDIAL PERFUSION IMAGING Bristol-Myers Squibb Pharma Company (US) 2007-07-04 EP disclosed
WO-2006044280-A1 COMPOUNDS FOR MYOCARDIAL PERFUSION IMAGING BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2006-04-27 WO disclosed
US-20060083681-A1 Compounds for myocardial perfusion imaging LANTHEUS MEDICAL IMAGING, INC. 2006-04-20 US disclosed
US-5801202-A Amine derivatives for treatment of skin disorders KAO COPRORATION (JP) 1998-09-01 US disclosed
EP-0790977-A1 AMINE DERIVATIVES FOR TREATMENT OF SKIN DISORDERS Kao Corporation (JP) 1997-08-27 EP disclosed
WO-1996015098-A1 AMINE DERIVATIVES FOR TREATMENT OF SKIN DISORDERS KAO CORPORATION (JP) 1996-05-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270505-A1 4-DIMETHYLAMINOBUTYRIC ACID DERIVATIVES CPT1B, CPT1A, CPT2 MEN1 2587/4885KMT2A 731/4885KDM4C 1718/4885
US-12060323-B2 6-hydroxy-3-hexenyl alkoxymethyl ether compound and a process for preparing a 3,13-octadecadien-1-ol compound from the same CYP8B1, CYP2E1, OXER1 MEN1 2297/4885KMT2A 960/4885KDM4C 356/4885
US-20250011287-A1 FLUORINE-CONTAINING COMPOUND AND CONTRAST AGENT AFF1, AFF2, ZRANB2 MEN1 117/4885KMT2A 1168/4885KDM4C 1000/4885
US-20240109924-A1 IP4-4,6 SUBSTITUTED DERIVATIVE COMPOUNDS IPO4, TPX2, IPO9 MEN1 2984/4885KMT2A 4555/4885KDM4C 1274/4885
US-20060083681-A1 Compounds for myocardial perfusion imaging TNNI3, FABP3, TNNT2 MEN1 1701/4885KMT2A 4785/4885KDM4C 4496/4885
US-12397058-B2 Metabolically stable prodrugs CES1, CES2, CYP2S1 MEN1 1968/4885KMT2A 3952/4885KDM4C 2044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.