SCHEMBL1009783

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1009580	0.89	CYP11B1 (0.51)	CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4
	SCHEMBL1012823	0.85	MAOA (0.46)	CYP2C9MAOAKDM4EDRD2TSHR
	SCHEMBL1009848	0.83	MAOA (0.47)	CYP11B1CYP11B2CYP2C9CYP3A4PDE3B
	SCHEMBL1009915	0.78	MAOA (0.43)	CYP11B2CYP2C9MAOAKDM4EDRD2
	SCHEMBL1009757	0.77	MAOA (0.46)	CYP2C9MAOAKDM4EDRD2TSHR
	SCHEMBL1012754	0.76	MAOA (0.49)	CYP2C9MAOAKDM4EDRD2TSHR
	SCHEMBL1011383	0.76	KDM1A (0.44)	CYP2C9MAOAKDM4EDRD2TSHR
	SCHEMBL1010787	0.76	ADRA2A (0.52)	CYP11B1CYP11B2CYP17A1CYP19A1
	SCHEMBL1009142	0.76	MAOA (0.43)	CYP2C9MAOAKDM4EDRD2TSHR
	SCHEMBL1010606	0.75	CYP2C19 (0.44)	CYP11B2CYP2C9CYP2C19MAOAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.