SCHEMBL1010606

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1010845	0.90	CYP2C19 (0.44)	CYP2C19GRIA2MAOADRD2TSHR
	SCHEMBL1010812	0.83	MAOA (0.46)	MAOADRD2TSHRKDM4ECYP2C9
	SCHEMBL1009142	0.78	MAOA (0.43)	MAOADRD2TSHRKDM4ECYP2C9
	SCHEMBL1011044	0.78	HTR2A (0.42)	—
	SCHEMBL8028189	0.77	GRIA2 (0.43)	CYP2C19GRIA2MAOACYP11B2BACE1
	SCHEMBL1009783	0.75	CYP11B1 (0.51)	CYP2C19MAOADRD2TSHRKDM4E
	SCHEMBL1009915	0.75	MAOA (0.43)	GRIA2MAOADRD2TSHRKDM4E
	SCHEMBL1009848	0.74	MAOA (0.47)	MAOADRD2TSHRKDM4ECYP2C9
	SCHEMBL1012214	0.73	MAOA (0.46)	MAOADRD2TSHRKDM4ECYP2C9
	SCHEMBL1011538	0.72	MAOA (0.43)	MAOADRD2TSHRKDM4ECYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.