SCHEMBL10098397

SCHEMBL10098397

Cc1ccc(-c2ccc([SiH](C)C)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.44
TDP1 Q9NUW8 2/20 0.44
ENPP3 O14638 1/20 0.40
ENPP1 P22413 1/20 0.40
GAA P10253 1/20 0.36
KIF11 P52732 1/20 0.35
ALDH1A1 P00352 4/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MCL1 Q07820 1/20 0.33
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476102 0.91 ACHE (0.53) ACHETDP1GAAALDH1A1CA1
SCHEMBL2579397 0.88 ALDH1A1 (0.32) TDP1ALDH1A1
SCHEMBL197731 0.78 ACHE (0.73) ACHETDP1ENPP3ENPP1KIF11
SCHEMBL148576 0.78
SCHEMBL2438805 0.78
SCHEMBL18661495 0.78 ACHE (0.73) ACHETDP1ENPP3ENPP1KIF11
SCHEMBL3287696 0.78 ACHE (0.73) ACHETDP1ENPP3ENPP1KIF11
SCHEMBL16075803 0.78 ALDH1A1 (0.50) TDP1KIF11ALDH1A1CA1CA2
SCHEMBL22182454 0.77 TEAD4 (0.54) ACHETDP1GAAALDH1A1CA1
SCHEMBL20077077 0.77 HPGD (0.56) ACHETDP1GAAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3679024-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-11-02 EP disclosed
WO-2019048443-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-03-14 WO disclosed
US-20140194019-A1 Silicone Composition, Silicone Adhesive, Coated and Laminated Substrates DOW CORNING CORPORATION (US) 2014-07-10 US disclosed
US-8207442-B2 Reinforcing structures for thin-film photovoltaic device substrates, and associated methods ITN ENERGY SYSTEMS, INC. (US) 2012-06-26 US disclosed