SCHEMBL2579397

SCHEMBL2579397

C[SiH](C)c1ccc(-c2ccc([SiH](C)C)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148576 0.89
SCHEMBL2438805 0.89
SCHEMBL10098397 0.88 ACHE (0.44) ALDH1A1TDP1
SCHEMBL19785007 0.86 CYP3A4 (0.58) ALDH1A1TP53CYP3A4TDP1
SCHEMBL19785204 0.84 L3MBTL1 (0.38) ALDH1A1CYP3A4TDP1
SCHEMBL23700583 0.82 HPGD (0.41) ESR1ESR2
SCHEMBL476102 0.76 ACHE (0.53) ALDH1A1TDP1
SCHEMBL21485125 0.73
SCHEMBL17656438 0.73 IDO1 (0.38)
SCHEMBL9761798 0.73 NR1H2 (0.43) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12187854-B2 Crosslinkable organosiloxane compositions WACKER CHEMIE AG (DE) 2025-01-07 US claimed
EP-4268018-A1 CHEMICALLY HOMOGENEOUS SILICON HARDMASKS FOR LITHOGRAPHY Brewer Science Inc. (US) 2023-11-01 EP claimed
WO-2022140621-A1 CHEMICALLY HOMOGENEOUS SILICON HARDMASKS FOR LITHOGRAPHY BREWER SCIENCE, INC. (US) 2022-06-30 WO claimed
US-20220195238-A1 CHEMICALLY HOMOGENEOUS SILICON HARDMASKS FOR LITHOGRAPHY BREWER SCIENCE, INC. 2022-06-23 US claimed
CN-111936556-B Crosslinkable organosiloxane compositions 瓦克化学股份公司 2022-05-03 CN claimed
US-8048977-B2 Organosilicon polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-01 US claimed
US-20090069525-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY 2009-03-12 US claimed
WO-2007130014-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-15 WO claimed
US-12497511-B2 Crosslinkable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2025-12-16 US disclosed
US-20250115700-A1 (METH)ACRYLATED HYPERBRANCHED POLYMERS, METHOD OF MAKING, COMPOSITIONS INCLUDING THE SAME, AND ELECTRONIC DEVICE 3M INNOVATIVE PROPERTIES COMPANY 2025-04-10 US disclosed
WO-2025052187-A1 HYPERBRANCHED POLYMERS FOR CURABLE HIGH REFRACTIVE INDEX COMPOSITIONS, ARTICLES THEREOF, AND METHODS OF MAKING SUCH ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-03-13 WO disclosed
US-12187854-B2 Crosslinkable organosiloxane compositions WACKER CHEMIE AG (DE) 2025-01-07 US disclosed
EP-4482889-A1 (METH)ACRYLATED HYPERBRANCHED POLYMERS, METHOD OF MAKING, COMPOSITIONS INCLUDING THE SAME, AND ELECTRONIC DEVICE 3M Innovative Properties Company (US) 2025-01-01 EP disclosed
US-12110393-B2 Crosslinkable organopolysiloxane compositions WACKER CHEMIE AG (DE) 2024-10-08 US disclosed
US-20130164517-A1 Hydrosilylation Cured Silicone Resins Plasticized By Organophosphorous Compounds DOW CORNING CORPORATION (US) 2013-06-27 US disclosed
US-20130149520-A1 PHOSPHOSILOXANE RESINS, AND CURABLE SILICONE COMPOSITIONS, FREE-STANDING FILMS, AND LAMINATES COMPRISING THE PHOSPHOSILOXANE RESINS DOW CORNING CORPORATION (US) 2013-06-13 US disclosed
US-8450442-B2 Borosiloxane composition, borosiloxane adhesive, coated and laminated substrates DOW CORNING CORPORATION (US) 2013-05-28 US disclosed
US-8048977-B2 Organosilicon polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-01 US disclosed
US-20090069525-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY 2009-03-12 US disclosed
WO-2007130014-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-15 WO disclosed