⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15304320 | 0.74 | — | — | |
| SCHEMBL20844132 | 0.72 | — | — | |
| SCHEMBL14253151 | 0.72 | — | — | |
| SCHEMBL77218 | 0.69 | — | — | |
| SCHEMBL21718699 | 0.69 | CNR1 (0.31) | — | |
| SCHEMBL21720478 | 0.69 | KMT2A (0.38) | — | |
| SCHEMBL2091229 | 0.67 | ALDH1A1 (0.39) | — | |
| SCHEMBL15304319 | 0.66 | ALDH1A1 (0.35) | — | |
| SCHEMBL5174730 | 0.65 | COMT (0.46) | — | |
| SCHEMBL9976517 | 0.65 | NOS1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024039858-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| WO-2020002091-A1 | SUBSTITUTED THIAZOLYLPYRROLONES, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019059161-A1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL GERMICIDE HAVING SAME AS ACTIVE INGREDIENT | 三井化学アグロ株式会社 | 2019-03-28 | — | — | WO | disclosed |
| US-9815850-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2017-11-14 | — | — | US | disclosed |
| WO-2017136727-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. (US) | 2017-08-10 | — | — | WO | disclosed |
| US-20170226127-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. | 2017-08-10 | — | — | US | disclosed |
| US-8207207-B2 | Heterocyclic a amide derivatives useful as microbiocides | SYNGENTA CROP PROTECTION LLC (US) | 2012-06-26 | — | — | US | disclosed |
| US-20100204287-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-12 | — | — | US | disclosed |
| US-7241721-B2 | carboxamide derivatives as active ingredients which have microbiocidal activity, in particular fungicidal activity | SYNGENTA CROP PROTECTION, INC. (US) | 2007-07-10 | — | — | US | disclosed |