Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13888468 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL10099684 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL11348296 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL11339493 | 0.79 | LMNA (0.46) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL201849 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL9448477 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL17843609 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL4107319 | 0.77 | KMT2A (0.47) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL13888475 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL2139392 | 0.76 | LMNA (0.42) | ALDH1A1HPGDKDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207365-B2 | Polymeric salen compounds and methods thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |