Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10099684 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDLMNAKDM4EKMT2A | |
| SCHEMBL15947780 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HPGDLMNAKMT2APOLB | |
| SCHEMBL4398747 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HPGDLMNAKDM4EKMT2A | |
| SCHEMBL11339493 | 0.81 | LMNA (0.46) | ALDH1A1HPGDLMNAKDM4EKMT2A | |
| SCHEMBL11348296 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAKDM4EKMT2A | |
| SCHEMBL13888468 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAKDM4EKMT2A | |
| SCHEMBL201849 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HPGDLMNAKDM4EKMT2A | |
| SCHEMBL17843609 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAKDM4EKMT2A | |
| SCHEMBL4107319 | 0.79 | KMT2A (0.47) | ALDH1A1HPGDLMNAKDM4EKMT2A | |
| SCHEMBL10099666 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDLMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325617-B1 | THIOLENE COMPOSITIONS BASED ON BICYCLIC 'ENE COMPOUNDS | LOCTITE CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0338616-A1 | Thiolene compositions based on bicyclic 'ene compounds | LOCTITE CORPORATION (US) | 1989-10-25 | — | — | EP | disclosed |
| EP-0325617-A1 | THIOLENE COMPOSITIONS BASED ON BICYCLIC 'ENE COMPOUNDS. | LOCTITE CORP (US) | 1989-08-02 | — | — | EP | disclosed |
| US-4808638-A | CROSSLINKING WITH POLYMERCAPTANS | LOCTITE CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| WO-1988002902-A2 | THIOLENE COMPOSITIONS BASED ON BICYCLIC 'ENE COMPOUNDS | LOCTITE CORPORATION (US) | 1988-04-21 | — | — | WO | disclosed |