Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24777901 | 0.84 | ADRA2A (0.61) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL1007796 | 0.81 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL30627606 | 0.80 | PKM (0.54) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL745193 | 0.80 | PKM (0.54) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL657416 | 0.79 | KDM1A (0.62) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL19278336 | 0.78 | APP (0.50) | NPC1RAB9ASMN1; SMN2PKMTP53 | |
| SCHEMBL1008711 | 0.77 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2PKMNFKB1 | |
| SCHEMBL12297526 | 0.77 | PTGS2 (0.87) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL1009963 | 0.77 | TRPV1 (0.62) | RAB9ASMN1; SMN2MAPTMAPK1TSHR | |
| SCHEMBL21933254 | 0.76 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1801104-B1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2011-01-05 | — | — | EP | claimed |
| EP-1801104-B1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2011-01-05 | — | — | EP | disclosed |