Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 7/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327849 | 0.79 | APP (0.63) | APPSNCAESR1ESR2RAB9A | |
| SCHEMBL3776968 | 0.74 | ALDH1A1 (0.68) | APPSNCAESR1ESR2RAB9A | |
| SCHEMBL5526914 | 0.71 | APP (0.70) | APPESR1ESR2MEN1KMT2A | |
| SCHEMBL3771904 | 0.71 | APP (0.55) | APPSNCAESR1ESR2RAB9A | |
| SCHEMBL13212103 | 0.70 | APP (0.57) | APPSNCAESR1ESR2RAB9A | |
| SCHEMBL10100298 | 0.70 | APP (0.48) | APPSNCAESR1ESR2RAB9A | |
| Lacmoid SCHEMBL2609260 | 0.69 | SNCA (0.81) | APPSNCAESR1ESR2RAB9A | |
| Lacmoid SCHEMBL29455251 | 0.69 | SNCA (0.81) | APPSNCAESR1ESR2RAB9A | |
| SCHEMBL8066 | 0.69 | APP (1.00) | APPSNCAESR1ESR2MEN1 | |
| SCHEMBL13521269 | 0.69 | SNCA (0.71) | APPSNCAESR1ESR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173698-B2 | Fluorescent probes; solid phase synthesis; kits | Life Technologies Corporation (US) | 2012-05-08 | — | — | US | disclosed |
| US-8173698-B2 | Fluorescent probes; solid phase synthesis; kits | Life Technologies Corporation (US) | 2012-05-08 | — | — | US | disclosed |
| US-20080160627-A1 | Environmental Sensitive Fluorogenic Compounds and Their Application for Singlet Oxygen and Protein Detection | INVITROGEN CORPORATION (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080160627-A1 | Environmental Sensitive Fluorogenic Compounds and Their Application for Singlet Oxygen and Protein Detection | INVITROGEN CORPORATION (US) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080160627-A1 | Environmental Sensitive Fluorogenic Compounds and Their Application for Singlet Oxygen and Protein Detection | PPOX, HSPE1, PRDX3 | APP 1762/4885SNCA 3980/4885ESR1 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.