SCHEMBL10100809

SCHEMBL10100809

Cc1c(C)c(-n2c3ccccc3c3ccccc32)c(C)c(C)c1-c1ccc(-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
KMT2A Q03164 2/20 0.39
HDAC4 P56524 1/20 0.38
GPR3 P46089 1/20 0.35
POLB P06746 1/20 0.34
PTPN1 P18031 2/20 0.33
LIG1 P18858 1/20 0.33
AKR1C4 P17516 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
AKR1C1 Q04828 1/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
MAPK8 P45983 1/20 0.33
IL1R1 P14778 1/20 0.33
LMNA P02545 1/20 0.33
HDAC6 Q9UBN7 2/20 0.32
RORC P51449 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10100818 0.93 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL13400015 0.86 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL12938579 0.84 KDM4E (0.41) L3MBTL1KDM4EATMKMT2AGPR3
SCHEMBL9890863 0.83 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL24169139 0.81 L3MBTL1 (0.55) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL13589122 0.80 KDM4E (0.43) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL10100823 0.80 KDM4E (0.50) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL275300 0.80 L3MBTL1 (0.64) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL12618513 0.80 GPR3 (0.54) L3MBTL1KDM4EATMKMT2AGPR3
SCHEMBL7601612 0.79 KDM4E (0.53) L3MBTL1KDM4EATMKMT2AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed