SCHEMBL10100817

SCHEMBL10100817

Cc1cc(-c2cc(C)c(-n3c4ccccc4c4ccccc43)cc2C)c(C)cc1-c1cc(C)c(-n2c3ccccc3c3ccccc32)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
ALDH1A1 P00352 3/20 0.41
GPR3 P46089 1/20 0.40
ALKBH5 Q6P6C2 1/20 0.39
FTO Q9C0B1 1/20 0.39
POLB P06746 1/20 0.38
NQO2 P16083 1/20 0.38
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
CYP1A2 P05177 2/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12938562 0.91 KDM4E (0.38) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL14823469 0.88 KDM4E (0.45) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL19269961 0.88 TSHR (0.36) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL20172751 0.87 KDM4E (0.37) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL12113713 0.86 KDM4E (0.46) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL13235733 0.85 ALDH1A1 (0.35) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL25638676 0.85 KDM4E (0.39) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL25638682 0.85 KDM4E (0.39) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL7605444 0.84 KDM4E (0.37) KDM4EL3MBTL1ATMALDH1A1GPR3
SCHEMBL18771369 0.84 TUBB4A (0.35) KDM4EL3MBTL1ATMALDH1A1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed