Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | TSPO | P30536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10100817 | 0.87 | KDM4E (0.42) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL12938562 | 0.86 | KDM4E (0.38) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL13620161 | 0.84 | TSPO (0.34) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL25643206 | 0.83 | HSD17B10 (0.42) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL13620139 | 0.82 | TSPO (0.34) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL7605444 | 0.82 | KDM4E (0.37) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL19269985 | 0.82 | L3MBTL1 (0.40) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL19269416 | 0.82 | L3MBTL1 (0.40) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL17589457 | 0.81 | HSD17B10 (0.41) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL13669430 | 0.81 | KDM4E (0.33) | KDM4EATML3MBTL1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10629817-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-04-21 | — | — | US | disclosed |
| US-20180145260-A1 | MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180145260-A1 | MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180145260-A1 | MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES | KCNB2, KCNB1, GJB2 | KDM4E 3737/4885ATM 2814/4885L3MBTL1 2807/4885 |
| US-10629817-B2 | Materials for organic electroluminescent devices | KCNB2, KCNB1, GJB2 | KDM4E 3816/4885ATM 3054/4885L3MBTL1 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.