SCHEMBL10100834

SCHEMBL10100834

Cc1nc(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)c(C)nc1-c1ccc(-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
HDAC4 P56524 1/20 0.39
MAPK1 P28482 2/20 0.39
HTT P42858 1/20 0.39
ALDH1A1 P00352 6/20 0.38
HPGD P15428 2/20 0.37
POLB P06746 2/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
NPY5R Q15761 2/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
GPR3 P46089 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HSD17B10 Q99714 2/20 0.36
GRIA1 P42261 1/20 0.36
CACNG8 Q8WXS5 1/20 0.36
CACNG2 Q9Y698 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12268535 0.89 KDM4E (0.44) KDM4EATML3MBTL1HDAC4MAPK1
SCHEMBL18777891 0.82 KDM4E (0.38) KDM4EATML3MBTL1HDAC4MEN1
SCHEMBL17879118 0.82 L3MBTL1 (0.55) KDM4EATML3MBTL1HDAC4MAPK1
SCHEMBL12207595 0.81 KDM4E (0.41) KDM4EATML3MBTL1MAPK1HTT
SCHEMBL11947027 0.81 KDM4E (0.46) KDM4EATML3MBTL1MAPK1HTT
SCHEMBL1303909 0.81 KDM4E (0.53) KDM4EATML3MBTL1HDAC4MAPK1
SCHEMBL14983265 0.80 KDM4E (0.40) KDM4EATML3MBTL1HDAC4MAPK1
SCHEMBL11947031 0.79 L3MBTL1 (0.52) KDM4EATML3MBTL1HDAC4MAPK1
SCHEMBL4883632 0.79 KDM4E (0.52) KDM4EATML3MBTL1HDAC4MAPK1
SCHEMBL16674360 0.79 L3MBTL1 (0.73) KDM4EATML3MBTL1HDAC4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
EP-2248870-A2 Organic electroluminscent element and display and illuminator Konica Minolta Holdings, Inc. (JP) 2010-11-10 EP disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed