SCHEMBL4883632

SCHEMBL4883632

c1ccc2nc(-c3ccc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc3)c(-c3ccc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc3)nc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
ATM Q13315 1/20 0.52
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
LMNA P02545 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
GAA P10253 1/20 0.44
DHODH Q02127 2/20 0.42
HDAC4 P56524 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MAPK10 P53779 1/20 0.41
MAPK14 Q16539 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HPGD P15428 2/20 0.40
POLB P06746 2/20 0.40
HSP90AA1 P07900 1/20 0.40
MAPT P10636 1/20 0.40
RAD51 Q06609 2/20 0.40
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1303909 0.98 KDM4E (0.53) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL36932 0.95 KDM4E (0.55) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL12690742 0.90 L3MBTL1 (0.46) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL19655330 0.90 L3MBTL1 (0.50) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL11987938 0.90 L3MBTL1 (0.46) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL12690741 0.90 L3MBTL1 (0.46) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL12690642 0.90 L3MBTL1 (0.46) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL6725348 0.90 L3MBTL1 (0.46) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL12690904 0.90 L3MBTL1 (0.46) KDM4EL3MBTL1ATMMEN1KMT2A
SCHEMBL6724694 0.90 L3MBTL1 (0.46) KDM4EL3MBTL1ATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328098-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-03 US disclosed
US-9328098-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-03 US disclosed
US-9328098-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-03 US disclosed
US-20150318492-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 US disclosed
US-20150318492-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 US disclosed
US-20150318492-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-05 US disclosed
US-9062036-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-23 US disclosed
US-9062036-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-23 US disclosed
US-9062036-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-23 US disclosed
US-20140228566-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-14 US disclosed
US-20140228566-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-14 US disclosed
US-8703305-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-04-22 US disclosed
US-8703305-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-04-22 US disclosed
US-8703305-B2 Quinoxaline derivative, and light emitting element, light emitting device, and electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-04-22 US disclosed
US-20120242936-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-27 US disclosed
US-20120242936-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-27 US disclosed
US-20120242936-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-27 US disclosed
US-20080079354-A1 Quinoxaline Derivative, And Light Emitting Element, Light Emitting Device, And Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-03 US disclosed
US-20080079354-A1 Quinoxaline Derivative, And Light Emitting Element, Light Emitting Device, And Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-03 US disclosed
US-20080079354-A1 Quinoxaline Derivative, And Light Emitting Element, Light Emitting Device, And Electronic Device Using the Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080079354-A1 Quinoxaline Derivative, And Light Emitting Element, Light Emitting Device, And Electronic Device Using the Quinoxaline Derivative NDUFV2, NDUFS8, NDUFA8 KDM4E 1813/4885L3MBTL1 1045/4885ATM 3730/4885
US-20140228566-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative NDUFV2, NDUFS8, NDUFA8 KDM4E 1813/4885L3MBTL1 1045/4885ATM 3730/4885
US-20150318492-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative NDUFV2, NDUFS8, NDUFA8 KDM4E 1813/4885L3MBTL1 1045/4885ATM 3730/4885
US-20120242936-A1 Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Quinoxaline Derivative NDUFV2, NDUFS8, NDUFA8 KDM4E 1813/4885L3MBTL1 1045/4885ATM 3730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.