SCHEMBL1303909

SCHEMBL1303909

c1ccc2nc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)c(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)nc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
ATM Q13315 1/20 0.53
LMNA P02545 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
GAA P10253 2/20 0.46
ALDH1A1 P00352 3/20 0.42
MAPK10 P53779 1/20 0.42
MAPK14 Q16539 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HPGD P15428 3/20 0.41
POLB P06746 2/20 0.41
RAD51 Q06609 2/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
HSD17B10 Q99714 2/20 0.40
GRIA1 P42261 1/20 0.40
CACNG8 Q8WXS5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4883632 0.98 KDM4E (0.52) KDM4EL3MBTL1ATMLMNATDP1
SCHEMBL36932 0.97 KDM4E (0.55) KDM4EL3MBTL1ATMLMNATDP1
SCHEMBL16271531 0.90 KDM4E (0.47) KDM4EL3MBTL1ATMLMNATDP1
SCHEMBL11947048 0.90 KDM4E (0.43) KDM4EL3MBTL1ATMLMNATDP1
SCHEMBL20886601 0.89 L3MBTL1 (0.51) KDM4EL3MBTL1ATMLMNATDP1
SCHEMBL17739642 0.89 KDM4E (0.46) KDM4EL3MBTL1ATMLMNATDP1
SCHEMBL17752700 0.88 KDM4E (0.53) KDM4EL3MBTL1ATMLMNATDP1
SCHEMBL11947029 0.88 KDM4E (0.48) KDM4EL3MBTL1ATMLMNATDP1
SCHEMBL17759776 0.88 L3MBTL1 (0.50) KDM4EL3MBTL1ATMLMNATDP1
SCHEMBL12690642 0.88 L3MBTL1 (0.46) KDM4EL3MBTL1ATMLMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10764974-B2 Light-emitting device using organometallic complex having a pyrazine skeleton SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-09-01 US disclosed
US-10764974-B2 Light-emitting device using organometallic complex having a pyrazine skeleton SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-09-01 US disclosed
US-20190053351-A1 Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-02-14 US disclosed
US-20190053351-A1 Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-02-14 US disclosed
US-10167303-B2 Iridium organometallic complex containing a substituted dibenzo[f,h]quinoxaline and an electronic device having an emitting layer containing the iridium complex UDC IRELAND LIMITED (IE) 2019-01-01 US disclosed
US-10167303-B2 Iridium organometallic complex containing a substituted dibenzo[f,h]quinoxaline and an electronic device having an emitting layer containing the iridium complex UDC IRELAND LIMITED (IE) 2019-01-01 US disclosed
US-10129947-B2 Light-emitting device using organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-11-13 US disclosed
US-10079350-B2 Organometallic complex, composition and light emitting element including the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-09-18 US disclosed
EP-2802594-B1 METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES UDC IRELAND LTD (IE) 2017-04-19 EP disclosed
US-20170044194-A1 Metal Complexes with Dibenzo[f,h]quinoxalines UDC IRELAND LTD (IE) 2017-02-16 US disclosed
EP-1973386-A2 Light-emitting device and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-09-24 EP disclosed
US-20080149923-A1 Light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-06-26 US disclosed
US-20080149923-A1 Light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-06-26 US disclosed
US-20080149923-A1 Light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-06-26 US disclosed
WO-2008065975-A1 LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-06-05 WO disclosed
US-20080079353-A1 Quinoxaline Derivative, And Light-Emitting Device, Electronic Device Using The Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-03 US disclosed
US-20080079353-A1 Quinoxaline Derivative, And Light-Emitting Device, Electronic Device Using The Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-03 US disclosed
US-20080079353-A1 Quinoxaline Derivative, And Light-Emitting Device, Electronic Device Using The Quinoxaline Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-03 US disclosed
EP-1905768-A1 Quinoxaline derivative, and light-emitting device, electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-02 EP disclosed
EP-1905768-A1 Quinoxaline derivative, and light-emitting device, electronic device using the quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10167303-B2 Iridium organometallic complex containing a substituted dibenzo[f,h]quinoxaline and an electronic device having an emitting layer containing the iridium complex NDUFS5, DDT, NDUFV2 KDM4E 1275/4885L3MBTL1 1863/4885ATM 3489/4885
US-10079350-B2 Organometallic complex, composition and light emitting element including the organometallic complex PPOX, RPL15, LAGE3 KDM4E 2700/4885L3MBTL1 2125/4885ATM 1583/4885
US-20170044194-A1 Metal Complexes with Dibenzo[f,h]quinoxalines NDUFS2, OCIAD2, NDUFS3 KDM4E 3445/4885L3MBTL1 2458/4885ATM 4417/4885
US-20080079353-A1 Quinoxaline Derivative, And Light-Emitting Device, Electronic Device Using The Quinoxaline Derivative HSF1, NQO2, NQO1 KDM4E 2188/4885L3MBTL1 1186/4885ATM 2140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.