SCHEMBL10100897

SCHEMBL10100897

FC(F)(F)C(c1ccc(-n2c3ccccc3c3ccccc32)cc1)(c1ccc(C(c2ccc(C(c3ccc(-n4c5ccccc5c5ccccc54)cc3)(C(F)(F)F)C(F)(F)F)cc2)(C(F)(F)F)C(F)(F)F)cc1)C(F)(F)F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ATM Q13315 1/20 0.55
KIF11 P52732 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
PPARG P37231 4/20 0.38
PPARA Q07869 3/20 0.38
PTPN1 P18031 2/20 0.35
TRPV1 Q8NER1 1/20 0.35
HDAC4 P56524 1/20 0.35
GPR3 P46089 1/20 0.34
MPI P34949 1/20 0.34
PHOSPHO1 Q8TCT1 1/20 0.34
DNM1 Q05193 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4570428 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMKIF11ESR1
SCHEMBL4570431 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMKIF11ESR1
SCHEMBL16481992 0.95 KDM4E (0.50) L3MBTL1KDM4EATMKIF11ESR1
SCHEMBL13589191 0.89 KDM4E (0.47) L3MBTL1KDM4EATMKIF11ESR1
SCHEMBL21168182 0.88 KDM4E (0.43) L3MBTL1KDM4EATMKIF11ESR1
SCHEMBL10100857 0.87 KDM4E (0.42) L3MBTL1KDM4EATMKIF11PPARG
SCHEMBL261854 0.87 MAOA (0.44) L3MBTL1KDM4EATMKIF11PPARG
SCHEMBL261896 0.87 KDM4E (0.42) L3MBTL1KDM4EATMKIF11
SCHEMBL4570446 0.87 MAOA (0.44) L3MBTL1KDM4EATMKIF11PPARG
SCHEMBL21168245 0.85 ATM (0.45) L3MBTL1KDM4EATMKIF11ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-8178214-B2 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-05-15 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed
US-20070184301-A1 Material for organic electroluminescence element, organic electroluminescence element, display device and illumination device KONICA MINOLTA HOLDINGS, INC. (JP) 2007-08-09 US disclosed