Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816877 | 1.00 | MAOB (0.51) | MAOBPTGESCCR5SLC5A2APP | |
| SCHEMBL30137004 | 0.85 | MEN1 (0.44) | MAOBCCR5SLC6A2SLC6A3HIF1A | |
| SCHEMBL27771937 | 0.85 | MEN1 (0.44) | MAOBCCR5SLC6A2SLC6A3HIF1A | |
| SCHEMBL1009096 | 0.83 | MAOB (0.51) | MAOBPTGESCCR5APPBCHE | |
| SCHEMBL27368089 | 0.82 | L3MBTL1 (0.44) | CCR5SLC5A2 | |
| SCHEMBL38651021 | 0.82 | L3MBTL1 (0.44) | CCR5SLC5A2 | |
| SCHEMBL28150597 | 0.82 | MAOB (0.55) | MAOBBCHELMNACYP1A2PTGS1 | |
| SCHEMBL38150 | 0.81 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL29386304 | 0.81 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL29816937 | 0.81 | MAOA (0.59) | MAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106892948-B | Glucopyranosyl derivative and application thereof in medicine | 宜昌东阳光长江药业股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| US-9394329-B2 | Glucopyranosyl derivatives and their uses in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-07-19 | — | — | US | disclosed |
| US-20150266916-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-09-24 | — | — | US | disclosed |
| CN-101998962-A | Novel aromatic fluoroglycoside derivatives, medicaments containing said compounds and the use thereof | SANOFI AVENTIS | 2011-03-30 | — | — | CN | disclosed |
| US-20110059910-A1 | Novel aromatic fluoroglycoside derivatives, pharmaceuticals comprising said compounds and the use thereof | SANOFI-AVENTIS (FR) | 2011-03-10 | — | — | US | disclosed |
| EP-2268653-A2 | NOVEL AROMATIC FLUOROGLYCOSIDE DERIVATIVES, PHARMACEUTICALS COMPRISING SAID COMPOUNDS, AND THE USE THEREOF | Sanofi-Aventis (FR) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009100936-A2 | NOVEL AROMATIC FLUOROGLYCOSIDE DERIVATIVES, PHARMACEUTICALS COMPRISING SAID COMPOUNDS, AND THE USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266916-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE | SLC5A2, SLC5A1, UGGT1 | MAOB 3066/4885PTGES 701/4885CCR5 1584/4885 |
| US-20110059910-A1 | Novel aromatic fluoroglycoside derivatives, pharmaceuticals comprising said compounds and the use thereof | SLC5A2, SLC5A1, SLC2A2 | MAOB 1135/4885PTGES 3061/4885CCR5 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.