SCHEMBL10102738

SCHEMBL10102738

COC(=O)CCCCCCCOc1ccccc1C(C)=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.68
SMN1; SMN2 Q16637 4/20 0.68
ALDH1A1 P00352 4/20 0.60
KDM4E B2RXH2 2/20 0.60
MAPT P10636 5/20 0.59
L3MBTL1 Q9Y468 3/20 0.59
HTT P42858 2/20 0.58
PPARG P37231 2/20 0.56
CNR2 P34972 2/20 0.55
POLB P06746 1/20 0.52
HPGD P15428 1/20 0.52
MEN1 O00255 1/20 0.51
NR1I2 O75469 1/20 0.51
CHRM2 P08172 1/20 0.51
CYP3A4 P08684 1/20 0.51
ADRA2A P08913 1/20 0.51
OPRK1 P41145 1/20 0.51
HTR2B P41595 1/20 0.51
SLC6A3 Q01959 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3783361 0.88 MAPT (0.56) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL13527398 0.86 LMNA (0.69) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL4266953 0.85 LMNA (0.68) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL5145231 0.85 LMNA (0.68) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL24395229 0.83 LMNA (0.69) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL29649457 0.83 LMNA (0.69) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL13313249 0.83 LMNA (0.79) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL11738774 0.81 LMNA (0.74) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL3962812 0.81 LMNA (0.74) LMNASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL15766523 0.81 LMNA (0.74) LMNASMN1; SMN2ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1478233-B1 METHOD FOR ADMINISTERING GLP-1 MOLECULES EMISPHERE TECH INC (US) 2016-11-09 EP disclosed
EP-2409569-A2 Method for administering GLP-1 molecules Emisphere Technologies, Inc. (US) 2012-01-25 EP disclosed