Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266953 | 1.00 | LMNA (0.68) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL2562760 | 0.94 | LMNA (0.68) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL13527398 | 0.89 | LMNA (0.69) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL2555648 | 0.89 | LMNA (0.70) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL2517739 | 0.87 | ALDH1A1 (0.65) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL19717846 | 0.87 | ALDH1A1 (0.65) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL5512491 | 0.87 | ALDH1A1 (0.65) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL5514981 | 0.85 | ALDH1A1 (0.67) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL13545502 | 0.85 | ALDH1A1 (0.61) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL10102738 | 0.85 | LMNA (0.68) | LMNASMN1; SMN2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE48164-E1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES INC. (US) | 2020-08-18 | — | — | US | disclosed |
| EP-2409569-B1 | Method for administering GLP-1 molecules | EMISPHERE TECH INC (US) | 2017-08-16 | — | — | EP | disclosed |
| EP-1478233-B1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | EMISPHERE TECH INC (US) | 2016-11-09 | — | — | EP | disclosed |
| US-20150202296-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2015-07-23 | — | — | US | disclosed |
| US-20150202296-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2015-07-23 | — | — | US | disclosed |
| US-8895777-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES INC (US) | 2014-11-25 | — | — | US | disclosed |
| US-8785381-B2 | Oral GLP-1 formulations | EMISPHERE TECHNOLOGIES, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785381-B2 | Oral GLP-1 formulations | EMISPHERE TECHNOLOGIES, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8492330-B2 | Formulation comprising GLP-1 | EMISPHERE TECHNOLOGIES, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| US-8492330-B2 | Formulation comprising GLP-1 | EMISPHERE TECHNOLOGIES, INC. (US) | 2013-07-23 | — | — | US | disclosed |
| US-20090286735-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2009-11-19 | — | — | US | disclosed |
| US-20090286735-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2009-11-19 | — | — | US | disclosed |
| EP-1972349-A1 | GLP-1 fusion peptides conjugated to polymer(s), their production and use | Biocompatibles UK Limited (GB) | 2008-09-24 | — | — | EP | disclosed |
| US-7309698-B2 | Compositions for delivering bisphosphonates | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309698-B2 | Compositions for delivering bisphosphonates | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309698-B2 | Compositions for delivering bisphosphonates | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-12-18 | — | — | US | disclosed |
| EP-1372667-A4 | COMPOSITIONS FOR DELIVERING BISPHOSPHONATES | EMISPHERE TECH INC (US) | 2007-03-14 | — | — | EP | disclosed |
| US-20040147484-A1 | Compositions for delivering bisphosphonates | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2004-07-29 | — | — | US | disclosed |
| EP-1372667-A2 | COMPOSITIONS FOR DELIVERING BISPHOSPHONATES | Emisphere Technologies, Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002070438-A2 | COMPOSITIONS FOR DELIVERING BISPHOSPHONATES | EMISPHERE TECHNOLOGIES, INC. (US) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150202296-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | GLP1R, GIPR, GPR119 | LMNA 4030/4885SMN1; SMN2 3138/4885ALDH1A1 3386/4885 |
| US-20040147484-A1 | Compositions for delivering bisphosphonates | PHOSPHO1, PTH1R, SOST | LMNA 1056/4885SMN1; SMN2 207/4885ALDH1A1 4697/4885 |
| US-20090286735-A1 | METHOD FOR ADMINISTERING GLP-1 MOLECULES | GLP1R, GIPR, GPR119 | LMNA 4030/4885SMN1; SMN2 3138/4885ALDH1A1 3386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.