Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.34 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19246833 | 0.76 | MME (0.58) | PTPN1ACEMMENPSR1L3MBTL1 | |
| SCHEMBL12069766 | 0.72 | ACE (0.50) | ACEPOLBMMEALDH1A1MAPT | |
| SCHEMBL24201035 | 0.69 | ACE (0.42) | PTPN1ACEPOLBMMEALDH1A1 | |
| SCHEMBL19968320 | 0.69 | ALDH1A1 (0.34) | ACEMMENPSR1ALDH1A1ACE2 | |
| SCHEMBL13862514 | 0.68 | KMT2A (0.44) | PTPN1ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL20877592 | 0.68 | KDM6B (0.36) | — | |
| SCHEMBL22503613 | 0.68 | GNPAT (0.45) | ACEPOLBMMEALDH1A1MEN1 | |
| SCHEMBL29033866 | 0.67 | KMT2A (0.58) | MMEL3MBTL1KMT2ANAALAD2CA2 | |
| SCHEMBL879605 | 0.67 | SLC7A5 (0.43) | POLBNPSR1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL23869542 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2409569-A2 | Method for administering GLP-1 molecules | Emisphere Technologies, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |