SCHEMBL879605

SCHEMBL879605

N[C@@H](CC1=CCCC=C1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.43
PKM P14618 2/20 0.43
PTGS1 P23219 2/20 0.43
ALPI P09923 1/20 0.43
XIAP P98170 1/20 0.43
USP2 O75604 3/20 0.40
HSD17B10 Q99714 3/20 0.40
ALOX15 P16050 2/20 0.40
HIF1A Q16665 2/20 0.40
KDM4E B2RXH2 2/20 0.40
RECQL P46063 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP3A4 P08684 2/20 0.40
RGS12 O14924 1/20 0.40
CYP2C9 P11712 1/20 0.40
NFKB1 P19838 1/20 0.40
CASP1 P29466 1/20 0.40
BRCA1 P38398 1/20 0.40
THPO P40225 1/20 0.40
CASP7 P55210 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3504346 1.00 SLC7A5 (0.43) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL22652556 0.86
SCHEMBL30531426 0.85 SLC7A5 (0.40) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL30531466 0.85 SLC7A5 (0.40) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL18567232 0.84 ALPI (0.31) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL20877592 0.80 KDM6B (0.36)
SCHEMBL12153681 0.79 APAF1 (0.33) HSD17B10KDM4ERECQLALDH1A1POLB
SCHEMBL25111145 0.78 ITGB3 (0.51) SLC7A5PKMPTGS1ALPIXIAP
SCHEMBL4623688 0.76 HDAC1 (0.31)
SCHEMBL27293069 0.74 SLC7A5 (0.53) SLC7A5PKMPTGS1ALPIXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1687401-B1 SITE-SPECIFIC INCORPORATION OF REDOX ACTIVE AMINO ACIDS INTO PROTEINS SCRIPPS RESEARCH INST (US) 2012-11-21 EP claimed
EP-1763535-B1 POLYPEPTIDE LINKED WITH AN ORGANIC GROUP JENNISSEN HERBERT P (DE) 2008-01-23 EP claimed
US-12569443-B2 Gastro-retentive drug delivery system APET Holding B.V. (NL) 2026-03-10 US disclosed
EP-4599695-A2 LIQUID NUTRITIONAL COMPOSITION SUITABLE FOR MUSCLE FUNCTION N.V. Nutricia (NL) 2025-08-13 EP disclosed
EP-4307923-B1 LIQUID NUTRITIONAL COMPOSITION SUITABLE FOR MUSCLE FUNCTION NUTRICIA NV (NL) 2025-06-25 EP disclosed
US-12178848-B2 Methods and compositions for the treatment of exocrine pancreatic insufficiency BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-12-31 US disclosed
US-20240299490-A1 LIQUID NUTRITIONAL COMPOSITION SUITABLE FOR MUSCLE FUNCTION N.V. NUTRICIA (NL) 2024-09-12 US disclosed
US-20240269215-A1 NUTRITIONAL COMPOSITION FOR MUSCLE MASS, STRENGTH AND FUNCTION N.V. NUTRICIA (NL) 2024-08-15 US disclosed
US-20240216293-A1 USE OF PERILLYL ALCOHOL TO ENHANCE LEVO-DOPA DELIVERY UNIVERSITY OF SOUTHERN CALIFORNIA 2024-07-04 US disclosed
US-20240209353-A1 NADK2 INHIBITION IN CANCER AND FIBROTIC DISORDERS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2024-06-27 US disclosed
EP-4380381-A1 NUTRITIONAL COMPOSITION FOR MUSCLE MASS, STRENGTH AND FUNCTION N.V. Nutricia (NL) 2024-06-12 EP disclosed
US-20020065274-A1 METHODS OF USING NOVEL COMPOUNDS AS NEURO-PROTECTIVE AGENTS PANETTA JILL ANN (US) 2002-05-30 US disclosed
US-6380213-B1 PHENYL OXAZOLES, THIAZOLES, OXAZOLINES, OXADIAZOLES AND BENZOXAZOLES ELI LILLY AND COMPANY 2002-04-30 US disclosed
US-20010027194-A1 NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS ELI LILLY AND COMPANY 2001-10-04 US disclosed
US-6166216-A Compounds useful as neuro-protective agents ELI LILLY AND COMPANY (US) 2000-12-26 US disclosed
US-6156748-A Compounds useful as neuro-protective agents ELI LILLY AND COMPANY (US) 2000-12-05 US disclosed
WO-1999018091-A1 NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS ELI LILLY AND COMPANY (US) 1999-04-15 WO disclosed
EP-0908454-A2 Oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents ELI LILLY AND COMPANY (US) 1999-04-14 EP disclosed
US-5476842-A Method and compositions for treating tumors having high tyrosinase activity CO ENZYME TECHNOLOGY LTD. (US) 1995-12-19 US disclosed
EP-0657469-A1 L-Selectin cleavage site, methods of diagnosis and usage thereof BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 1995-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569443-B2 Gastro-retentive drug delivery system GYS2, ABCB11, GYS1 SLC7A5 49/4885PKM 555/4885PTGS1 73/4885
US-20240216293-A1 USE OF PERILLYL ALCOHOL TO ENHANCE LEVO-DOPA DELIVERY SNCA, SLC18A2, SLC18A3 SLC7A5 345/4885PKM 2021/4885PTGS1 3587/4885
US-20010027194-A1 NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS NLN, PRDX5, TXN2 SLC7A5 2964/4885PKM 2604/4885PTGS1 380/4885
US-20020065274-A1 METHODS OF USING NOVEL COMPOUNDS AS NEURO-PROTECTIVE AGENTS NLN, GAP43, TXN2 SLC7A5 4054/4885PKM 2508/4885PTGS1 453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.