Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 7/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5260684 | 0.84 | CA2 (0.70) | KMT2ACA2CA1MMP2MMP9 | |
| SCHEMBL5260686 | 0.84 | CA2 (0.70) | KMT2ACA2CA1MMP2MMP9 | |
| SCHEMBL2246061 | 0.78 | CA2 (0.69) | KMT2ACA2CA1MMP2MMP9 | |
| SCHEMBL2245325 | 0.78 | CA2 (0.69) | KMT2ACA2CA1MMP2MMP9 | |
| SCHEMBL6256233 | 0.77 | CA2 (0.54) | KMT2ACA2CA1MMP2MMP9 | |
| SCHEMBL2248738 | 0.77 | HPGDS (0.60) | KMT2ACA2CA1MMP2MMP9 | |
| SCHEMBL11519163 | 0.77 | CA2 (0.60) | KMT2ACA2CA1C3AR1 | |
| SCHEMBL19246833 | 0.76 | MME (0.58) | CA2CA1NAALAD2MMEL3MBTL1 | |
| SCHEMBL2242569 | 0.76 | CA2 (0.63) | KMT2ACA2CA1C3AR1 | |
| SCHEMBL20334999 | 0.76 | KMT2A (0.74) | KMT2ACA2CA1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116429952-B | Depression marker, application thereof in depression diagnosis and evaluation device | 深圳市第二人民医院(深圳市转化医学研究院) | 2024-02-02 | — | — | CN | disclosed |
| CN-116429952-A | Depression marker, application thereof in depression diagnosis and evaluation device | 深圳市第二人民医院(深圳市转化医学研究院) | 2023-07-14 | — | — | CN | disclosed |