Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503884 | 0.91 | CYP3A4 (0.62) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL14750866 | 0.90 | CYP3A4 (0.78) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL20436815 | 0.87 | CYP3A4 (0.58) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL10145566 | 0.85 | CYP3A4 (0.46) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL10103168 | 0.84 | FTO (0.70) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL31433112 | 0.84 | FTO (0.70) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL31432985 | 0.83 | CYP3A4 (0.68) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL10103163 | 0.83 | CYP3A4 (0.68) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL28545013 | 0.83 | CYP3A4 (0.67) | CYP3A4MAPTMEN1KMT2ALMNA | |
| SCHEMBL10145582 | 0.82 | CYP3A4 (0.44) | CYP3A4MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027337-A1 | BIOORTHOGONAL REACTION OF AN AMINE N-OXIDE AND A BORON AGENT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-16 | — | — | WO | disclosed |
| EP-2250177-B1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LTD (CN) | 2014-06-18 | — | — | EP | disclosed |
| US-8148423-B2 | Fluorophore compounds | VERSITECH LIMITED (CN) | 2012-04-03 | — | — | US | disclosed |
| US-8148423-B2 | Fluorophore compounds | VERSITECH LIMITED (CN) | 2012-04-03 | — | — | US | disclosed |
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | disclosed |
| US-20090253143-A1 | FLUOROPHORE COMPOUNDS | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | disclosed |
| US-20090253143-A1 | FLUOROPHORE COMPOUNDS | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | disclosed |
| WO-2009121244-A1 | FLUOROPHORE COMPOUNDS | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009121247-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | ROS1, LPO, HMOX1 | CYP3A4 508/4885MAPT 4349/4885MEN1 4478/4885 |
| US-20090253143-A1 | FLUOROPHORE COMPOUNDS | FUCA1, DNA2, LRAT | CYP3A4 2014/4885MAPT 1858/4885MEN1 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.