Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 6/20 | 0.54 |
| ▸ | REN | P00797 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PEPD | P12955 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010333 | 1.00 | RAB9A (1.00) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL1012705 | 1.00 | RAB9A (1.00) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL21225551 | 0.95 | RAB9A (0.91) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL21241511 | 0.95 | RAB9A (0.91) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL18190844 | 0.90 | RAB9A (0.82) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL7877696 | 0.90 | RAB9A (0.82) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL3680005 | 0.88 | RAB9A (0.78) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL3680002 | 0.88 | RAB9A (0.78) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL15148125 | 0.85 | RAB9A (0.74) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL8544043 | 0.84 | RAB9A (0.72) | RAB9AHTTTSHRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020037559-A1 | PROCESS FOR PRODUCING N-PROTECTED D-PROLINE DERIVATIVES | LONZA A.G. (CH) | 2002-03-28 | — | — | US | claimed |
| EP-0896617-A1 | PROCESS FOR PRODUCING N-PROTECTED D-PROLINE DERIVATIVES | LONZA AG (CH) | 1999-02-17 | — | — | EP | claimed |
| WO-1997033987-A1 | PROCESS FOR PRODUCING N-PROTECTED D-PROLINE DERIVATIVES | LONZA AG (CH) | 1997-09-18 | — | — | WO | claimed |
| EP-4139295-B1 | ISOQUINILINE NRF2 AGONISTS | C4X DISCOVERY LTD (GB) | 2025-04-09 | — | — | EP | disclosed |
| EP-1824876-B1 | PANCREATIC POLYPEPTIDE FAMILY MOTIFS, POLYPEPTIDES AND METHODS COMPRISING THE SAME | AMYLIN PHARMACEUTICALS LLC (US) | 2015-07-29 | — | — | EP | disclosed |
| US-8012963-B2 | 3,4-dihydro-2H-benzo[1,4]oxazine and thiazine derivatives as CETP inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-09-06 | — | — | US | disclosed |
| US-20110212956-A1 | Pyrazolopyrimidines for treating CNS disorders | MERZ PHARMA GMBH & CO. KGAA (DE) | 2011-09-01 | — | — | US | disclosed |
| US-7985753-B2 | Substituted pyrazolo[1,5-A]pyrimidines as metabotropic glutamate receptor modulators | MERZ PHARMA GMBH & CO. KGAA (DE) | 2011-07-26 | — | — | US | disclosed |
| EP-2295439-A1 | Substituted pyrazolopyrimidines, a process for their preparation and their use as medicine | Merz Pharma GmbH & Co. KGaA (DE) | 2011-03-16 | — | — | EP | disclosed |
| EP-2054416-B1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO KGAA (DE) | 2011-01-05 | — | — | EP | disclosed |
| US-20100227857-A1 | 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE AND THIAZINE DERIVATIVES AS CETP INHIBITORS | KUO GEE-HONG | 2010-09-09 | — | — | US | disclosed |
| EP-1758866-A1 | PROCESSES FOR PREPARING 6-ALKYL-5-ARYLSULFONYL- DIHYDROPHENANTHRIDINES | Wyeth (US) | 2007-03-07 | — | — | EP | disclosed |
| US-20060025436-A1 | Processes for preparing 6-alkyl-5-arylsulfonyl-dihydrophenanthridines | WYETH (US) | 2006-02-02 | — | — | US | disclosed |
| WO-2006009831-A1 | PROCESSES FOR PREPARING 6-ALKYL-5-ARYLSULFONYL- DIHYDROPHENANTHRIDINES | WYETH (US) | 2006-01-26 | — | — | WO | disclosed |
| US-20020037559-A1 | PROCESS FOR PRODUCING N-PROTECTED D-PROLINE DERIVATIVES | LONZA A.G. (CH) | 2002-03-28 | — | — | US | disclosed |
| EP-0896617-A1 | PROCESS FOR PRODUCING N-PROTECTED D-PROLINE DERIVATIVES | LONZA AG (CH) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997033987-A1 | PROCESS FOR PRODUCING N-PROTECTED D-PROLINE DERIVATIVES | LONZA AG (CH) | 1997-09-18 | — | — | WO | disclosed |
| EP-0273399-B1 | Optically active 2,3-dihydrobenzoaxine derivatives and process for preparing the same | DAIICHI SEIYAKU CO (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-4895944-A | BACTERICIDE OFLOXACIN | DAIICHI SEIYAKU COMPANY, LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0273399-A1 | Optically active 2,3-dihydrobenzoaxine derivatives and process for preparing the same | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227857-A1 | 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE AND THIAZINE DERIVATIVES AS CETP INHIBITORS | CETP, MTTP, CES1 | RAB9A 4606/4885HTT 3883/4885TSHR 4323/4885 |
| US-20060025436-A1 | Processes for preparing 6-alkyl-5-arylsulfonyl-dihydrophenanthridines | QDPR, RPS9, RPS4Y1 | RAB9A 99/4885HTT 513/4885TSHR 992/4885 |
| US-20110212956-A1 | Pyrazolopyrimidines for treating CNS disorders | GRM5, GRM3, GRM1 | RAB9A 1347/4885HTT 1894/4885TSHR 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.