Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.82 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 6/20 | 0.42 |
| ▸ | REN | P00797 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877696 | 1.00 | RAB9A (0.82) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL1010332 | 0.90 | RAB9A (1.00) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL1012705 | 0.90 | RAB9A (1.00) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL1010333 | 0.90 | RAB9A (1.00) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL21241511 | 0.89 | RAB9A (0.91) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL21225551 | 0.89 | RAB9A (0.91) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL25414655 | 0.82 | RAB9A (0.57) | RAB9ATSHRALDH1A1GAAACE | |
| SCHEMBL7871571 | 0.82 | RAB9A (0.57) | RAB9ATSHRALDH1A1GAAACE | |
| SCHEMBL3680005 | 0.78 | RAB9A (0.78) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL3680002 | 0.78 | RAB9A (0.78) | RAB9AHTTTSHRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |