Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 6/20 | 0.35 |
| ▸ | KDM4A | O75164 | 4/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104068 | 0.84 | KDM4A (0.38) | CHATMEN1USP2ALDH1A1MAPT | |
| SCHEMBL10104062 | 0.81 | KDM4E (0.36) | KDM4E | |
| SCHEMBL16070411 | 0.81 | CHAT (0.30) | CHAT | |
| SCHEMBL1825826 | 0.80 | RAB9A (0.40) | CHATMEN1USP2ALDH1A1LMNA | |
| SCHEMBL1825824 | 0.80 | RAB9A (0.40) | CHATMEN1USP2ALDH1A1LMNA | |
| SCHEMBL12657096 | 0.80 | CHAT (0.44) | CHATMEN1USP2ALDH1A1LMNA | |
| SCHEMBL10104065 | 0.80 | ALDH1A1 (0.46) | CHATMEN1USP2ALDH1A1LMNA | |
| SCHEMBL19649014 | 0.77 | KDM4A (0.39) | CHATMEN1USP2ALDH1A1LMNA | |
| SCHEMBL16104221 | 0.77 | — | — | |
| SCHEMBL12657267 | 0.75 | CHAT (0.47) | CHATMEN1USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004759-B1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | ORÉAL L (FR) | 2016-05-11 | — | — | EP | disclosed |
| US-8097044-B2 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping and dyeing processes | L'OREAL S.A. (FR) | 2012-01-17 | — | — | US | disclosed |
| US-8038731-B2 | hair dyes contains naphthylimide thiol or disulphide groups; resistant and visible lightening effect on dark keratin fibres; cosmetics | L'OREAL S.A. (FR) | 2011-10-18 | — | — | US | disclosed |
| US-20090313769-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | L'OREAL S.A. (FR) | 2009-12-24 | — | — | US | disclosed |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | KRT18, DSG1, ALPG | CHAT 1316/4885MEN1 3833/4885USP2 2451/4885 |
| US-20090313769-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | KRT18, DSG1, KRTCAP2 | CHAT 2618/4885MEN1 3694/4885USP2 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.