Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | MEN1 | O00255 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | INSR | P06213 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10104061 | 0.87 | APP (0.32) | APPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL17733967 | 0.86 | — | — | |
| SCHEMBL10104081 | 0.81 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10104073 | 0.81 | KDM4A (0.50) | APPCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10104067 | 0.77 | POLB (0.31) | POLB | |
| SCHEMBL10104066 | 0.76 | ALDH1A1 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10104069 | 0.74 | CHRM2 (0.54) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10104083 | 0.74 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12215963 | 0.73 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL12657235 | 0.73 | APP (0.33) | APPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004759-B1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | ORÉAL L (FR) | 2016-05-11 | — | — | EP | disclosed |
| EP-2781556-A1 | Method of colouring and lightening keratin materials in the presence of a reducing agent comprising a fluorescent disulphide dye | L'Oréal (FR) | 2014-09-24 | — | — | EP | disclosed |
| EP-2018847-B1 | Hair composition comprising at least one direct disulfide dye and at least one alkali hydroxide agent and method of simultaneous styling and dyeing. | ORÉAL L (FR) | 2014-09-17 | — | — | EP | disclosed |
| US-20140033450-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DEISULPHIDE DYE | L'OREAL (FR) | 2014-02-06 | — | — | US | disclosed |
| US-8562693-B2 | Method of dyeing and lightening keratin materials in the presence of a reducing agent comprising a fluorescent deisulphide dye | L'OREAL (FR) | 2013-10-22 | — | — | US | disclosed |
| US-20130074276-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | L'OREAL S.A. (FR) | 2013-03-28 | — | — | US | disclosed |
| US-8328880-B2 | Method of colouring and lightening keratin materials in the presence of a reducing agent comprising a fluorescent disulphide dye | L'OREAL (FR) | 2012-12-11 | — | — | US | disclosed |
| US-20120177587-A1 | METHOD OF COLOURING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | L'ORéAL S.A. | 2012-07-12 | — | — | US | disclosed |
| US-8097044-B2 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping and dyeing processes | L'OREAL S.A. (FR) | 2012-01-17 | — | — | US | disclosed |
| US-8038731-B2 | hair dyes contains naphthylimide thiol or disulphide groups; resistant and visible lightening effect on dark keratin fibres; cosmetics | L'OREAL S.A. (FR) | 2011-10-18 | — | — | US | disclosed |
| US-20090313769-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | L'OREAL S.A. (FR) | 2009-12-24 | — | — | US | disclosed |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
| EP-2018847-A1 | Hair composition comprising at least one direct disulfide dye and at least one alkali hydroxide agent and method of simultaneous styling and dyeing. | L'Oreal (FR) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007110534-A2 | DYEING COMPOSITION COMPRISING A THIOL/DISULPHIDE FLUORESCENT COLORANT HAVING AN EXTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID COLORANT | L'ORÉAL (FR) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007110542-A2 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | L'OREAL (FR) | 2007-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120177587-A1 | METHOD OF COLOURING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | KRT18, DSG1, KRTCAP2 | APP 2276/4885CHRM2 4369/4885CHRM4 4064/4885 |
| US-20090126755-A1 | Hair compositions comprising at least one disulfide direct dye and at least one alkaline hydroxide agent and simultaneous hair shaping an dyeing processes | KRT18, DSG1, ALPG | APP 1174/4885CHRM2 4532/4885CHRM4 4159/4885 |
| US-20140033450-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DEISULPHIDE DYE | KRT18, DSG1, DSP | APP 2434/4885CHRM2 4446/4885CHRM4 3988/4885 |
| US-20130074276-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | KRT18, DSG1, KRTCAP2 | APP 1953/4885CHRM2 4386/4885CHRM4 4040/4885 |
| US-20090313769-A1 | METHOD OF DYEING AND LIGHTENING KERATIN MATERIALS IN THE PRESENCE OF A REDUCING AGENT COMPRISING A FLUORESCENT DISULPHIDE DYE | KRT18, DSG1, KRTCAP2 | APP 1953/4885CHRM2 4386/4885CHRM4 4040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.