SCHEMBL10104175

SCHEMBL10104175

C=CC(=O)N(CCC[Si](CC(C)C)(OC(C)C)C(C)C)CCC[Si](CC(C)C)(OC(C)C)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283843 0.80 ZDHHC20 (0.36) ZDHHC20ZDHHC2
SCHEMBL10104173 0.76
SCHEMBL13609159 0.75 ZDHHC20 (0.40) ZDHHC20ZDHHC2TSHR
SCHEMBL8765207 0.69 ZDHHC20 (0.44) ZDHHC20ZDHHC2TSHR
SCHEMBL4316811 0.68 ZDHHC20 (0.41) ZDHHC20ZDHHC2
SCHEMBL8765499 0.68 ZDHHC20 (0.46) ZDHHC20ZDHHC2TSHR
SCHEMBL9362963 0.66 ZDHHC20 (0.49) ZDHHC20ZDHHC2TSHR
SCHEMBL17689808 0.66 ZDHHC20 (0.39) ZDHHC20ZDHHC2TSHR
SCHEMBL17693473 0.66 ZDHHC20 (0.39) ZDHHC20ZDHHC2TSHR
SCHEMBL15655347 0.66 ZDHHC20 (0.42) ZDHHC20ZDHHC2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546257-B2 Porous carbon-heteroatom-silicon inorganic/organic materials for chromatographic separations and process for the preparation thereof WATERS TECHNOLOGIES CORPORATION (US) 2017-01-17 US disclosed
US-20160263555-A1 COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION 2016-09-15 US disclosed
US-9248383-B2 Composite materials containing nanoparticles and their use in chromatography WATERS TECHNOLOGIES CORPORATION (US) 2016-02-02 US disclosed
US-9120083-B2 Porous inorganic/organic hybrid particles having high organic content and enhanced pore geometry for chromatographic separations WATERS TECHNOLOGIES CORPORATION (US) 2015-09-01 US disclosed
US-20140228464-A1 POROUS CARBON-HETEROATOM-SILICON INORGANIC/ORGANIC MATERIALS FOR CHROMATOGRAPHIC SEPARATIONS AND PROCESS FOR THE PREPARATION THEREOF WATERS TECHNOLOGIES CORPORATION (US) 2014-08-14 US disclosed
US-20120141789-A1 POROUS INORGANIC/ORGANIC HYBRID PARTICLES HAVING HIGH ORGANIC CONTENT AND ENHANCED PORE GEOMETRY FOR CHROMATOGRAPHIC SEPARATIONS WATERS INVESTMENTS LIMITED (US) 2012-06-07 US disclosed
US-20110049056-A1 COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION (US) 2011-03-03 US disclosed
US-20100076103-A1 POROUS CARBON-HETEROATOM-SILICON HYBRID INORGANIC/ORGANIC MATERIALS FOR CHROMATOGRAPHIC SEPARATIONS AND PROCESS FOR THE PREPARATION THEREOF WATERS INVESTMENTS LIMITED (US) 2010-03-25 US disclosed